Source:http://linkedlifedata.com/resource/pubmed/id/19579422
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
206
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pubmed:dateCreated |
2009-7-7
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pubmed:abstractText |
Type 1 diabetes currently affects 15,000 patients in Switzerland with a rising incidence worldwide. Pancreas or islet of Langerhans transplantation are alternatives to intensive insulin treatment, which decreases long-term complications at the cost of an increase of severe hyoglycemia. Pancreas transplantation, indicated mainly to diabetic patients with simultaneous kidney transplantation, has a high success rate, but is accompanied by high morbidity due to general surgery. Islet transplantation, a cell-therapy for type 1 diabetes, is in full development. It is mainly indicated as islet transplant alone in patients suffering from brittle diabetes, and is associated with a very low risk due to minimally invasive technique, but a lower rate of long-term success. New potential sources of beta cell replacement are beta-cell lines, stem cells and xenotransplantation.
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pubmed:language |
fre
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1660-9379
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
3
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pubmed:volume |
5
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1266-70, 1272
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pubmed:meshHeading | |
pubmed:year |
2009
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pubmed:articleTitle |
[Pancreas and islets of Langerhans transplantation: current status in 2009 and perspectives].
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pubmed:affiliation |
Laboratoire d'isolement et de transplantation cellulaire CMU, 1211 Genève 4.
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pubmed:publicationType |
Journal Article,
English Abstract
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