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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
11
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pubmed:dateCreated |
2009-10-5
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pubmed:abstractText |
Morphometric endophenotypes which have been proposed for psychotic disorders include lateral ventricular enlargement and hippocampal volume reductions. Genetic epidemiological studies support an overlap between schizophrenia and bipolar disorder, and COMT, BDNF, 5-HTT, NRG1 and DTNBP1 genes have been implicated in the aetiology of both these disorders. This study examined associations between these candidate genes and morphometric endophenotypes for psychosis.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Brain-Derived Neurotrophic Factor,
http://linkedlifedata.com/resource/pubmed/chemical/Carrier Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Catechol O-Methyltransferase,
http://linkedlifedata.com/resource/pubmed/chemical/DTNBP1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/NRG1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Neuregulin-1,
http://linkedlifedata.com/resource/pubmed/chemical/SLC6A4 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Serotonin Plasma Membrane...
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1469-8978
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pubmed:author |
pubmed-author:AllinMM,
pubmed-author:BramonEE,
pubmed-author:CollierDD,
pubmed-author:DempsterEE,
pubmed-author:DuttAA,
pubmed-author:MarshallNN,
pubmed-author:McDonaldCC,
pubmed-author:MurrayRR,
pubmed-author:PratoRR,
pubmed-author:SchulzeKK,
pubmed-author:ShaikhMM,
pubmed-author:WalsheMM,
pubmed-author:WilliamsII
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pubmed:issnType |
Electronic
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pubmed:volume |
39
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1783-97
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pubmed:meshHeading |
pubmed-meshheading:19573260-Adolescent,
pubmed-meshheading:19573260-Adult,
pubmed-meshheading:19573260-Aged,
pubmed-meshheading:19573260-Bipolar Disorder,
pubmed-meshheading:19573260-Brain-Derived Neurotrophic Factor,
pubmed-meshheading:19573260-Carrier Proteins,
pubmed-meshheading:19573260-Catechol O-Methyltransferase,
pubmed-meshheading:19573260-Dominance, Cerebral,
pubmed-meshheading:19573260-Female,
pubmed-meshheading:19573260-Genetic Association Studies,
pubmed-meshheading:19573260-Genotype,
pubmed-meshheading:19573260-Hippocampus,
pubmed-meshheading:19573260-Humans,
pubmed-meshheading:19573260-Lateral Ventricles,
pubmed-meshheading:19573260-Magnetic Resonance Imaging,
pubmed-meshheading:19573260-Male,
pubmed-meshheading:19573260-Middle Aged,
pubmed-meshheading:19573260-Neuregulin-1,
pubmed-meshheading:19573260-Organ Size,
pubmed-meshheading:19573260-Phenotype,
pubmed-meshheading:19573260-Polymorphism, Genetic,
pubmed-meshheading:19573260-Polymorphism, Single Nucleotide,
pubmed-meshheading:19573260-Psychotic Disorders,
pubmed-meshheading:19573260-Reference Values,
pubmed-meshheading:19573260-Schizophrenia,
pubmed-meshheading:19573260-Serotonin Plasma Membrane Transport Proteins,
pubmed-meshheading:19573260-Young Adult
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pubmed:year |
2009
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pubmed:articleTitle |
The effect of COMT, BDNF, 5-HTT, NRG1 and DTNBP1 genes on hippocampal and lateral ventricular volume in psychosis.
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pubmed:affiliation |
NIHR Biomedical Research Centre, Institute of Psychiatry (King's College London)/South London and Maudsley NHS Foundation Trust, London, UK. Anirban.Dutt@kcl.ac.uk
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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