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rdf:type |
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lifeskim:mentions |
umls-concept:C0032659,
umls-concept:C0085228,
umls-concept:C0871261,
umls-concept:C1269683,
umls-concept:C1335073,
umls-concept:C1417821,
umls-concept:C1537647,
umls-concept:C1556094,
umls-concept:C1704632,
umls-concept:C1706817,
umls-concept:C2911692
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pubmed:issue |
4
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pubmed:dateCreated |
2009-8-17
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pubmed:abstractText |
Sleep-wake disturbance, frequently observed in major depressive disorder (MDD), negatively influences clinical status. Treatment with antidepressants also reportedly affects circadian rhythms. In a recent in vitro study, the nuclear receptor Rev-erbalpha was reported to be related to circadian rhythms, and was shown to be involved in the biological action of lithium therapy. Therefore, we examined the association between the orphan nuclear receptor Rev-erbalpha gene (NR1D1) and the efficacy of fluvoxamine treatment in 118 Japanese patients with major depressive disorder.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1423-0224
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pubmed:author |
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pubmed:copyrightInfo |
Copyright 2009 S. Karger AG, Basel.
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pubmed:issnType |
Electronic
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pubmed:volume |
59
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
234-8
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:19571598-Adult,
pubmed-meshheading:19571598-Antidepressive Agents, Second-Generation,
pubmed-meshheading:19571598-Depressive Disorder, Major,
pubmed-meshheading:19571598-Female,
pubmed-meshheading:19571598-Fluvoxamine,
pubmed-meshheading:19571598-Gene Frequency,
pubmed-meshheading:19571598-Genotype,
pubmed-meshheading:19571598-Haplotypes,
pubmed-meshheading:19571598-Humans,
pubmed-meshheading:19571598-Japan,
pubmed-meshheading:19571598-Linkage Disequilibrium,
pubmed-meshheading:19571598-Male,
pubmed-meshheading:19571598-Middle Aged,
pubmed-meshheading:19571598-Nuclear Receptor Subfamily 1, Group D, Member 1,
pubmed-meshheading:19571598-Polymorphism, Single Nucleotide,
pubmed-meshheading:19571598-Receptors, Cytoplasmic and Nuclear,
pubmed-meshheading:19571598-Remission Induction,
pubmed-meshheading:19571598-Sequence Analysis, DNA,
pubmed-meshheading:19571598-Severity of Illness Index,
pubmed-meshheading:19571598-Treatment Outcome
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pubmed:year |
2009
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pubmed:articleTitle |
Orphan nuclear receptor Rev-erb alpha gene (NR1D1) and fluvoxamine response in major depressive disorder in the Japanese population.
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pubmed:affiliation |
Department of Psychiatry, Fujita Health University School of Medicine, Toyoake, Japan. tarok@fujita-hu.ac.jp
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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