Linked Life Data

19570644

Source:http://linkedlifedata.com/resource/pubmed/id/19570644

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2009-7-20
pubmed:abstractText
Ethanolic extracts of Achillea ligustica All. (Asteraceae) flowering tops were evaluated. High-performance liquid chromatography-electrospray ionisation-mass spectrometry was used for the identification and quantification of phenolic compounds. 6-Hydroxykaempferol-3,6,4'-trimethyl ether, apigenin-6-C-glucoside-8-C-arabinoside, luteolin, and apigenin were the most abundant flavonoids. For the first time C-glycosylflavones were detected in A. ligustica with apigenin-6-C-glucoside-8-C-arabinoside being the most representative. The radical scavenging activity of the extracts was determined by DPPH test and ranged between 4.18 and 12.3 mM. The ability of these extracts to inhibit non-enzymatic lipid peroxidation was studied using the simple in vitro system of linoleic acid oxidation: five of the nine extracts exerted a protective effect at the lower amount tested (5 microg). Protection on CaCo-2 intestinal cells against TBH-induced toxicity was also investigated: the results showed that two of the extracts tested in this cell system had the ability to protect against oxidative stress induced by TBH starting from concentrations as low as 10 microg/ml.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
1873-264X
pubmed:author
pubmed:issnType
Electronic
pubmed:day
15
pubmed:volume
50
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
440-8
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Flavonoid characterization and antioxidant activity of hydroalcoholic extracts from Achillea ligustica All.
pubmed:affiliation
Dipartimento di Tossicologia, University of Cagliari, via Ospedale 72, 09124 Cagliari, Italy. tuberoso@unica.it
pubmed:publicationType
Journal Article