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rdf:type |
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lifeskim:mentions |
umls-concept:C0002351,
umls-concept:C0015031,
umls-concept:C0017337,
umls-concept:C0017837,
umls-concept:C0034897,
umls-concept:C0035647,
umls-concept:C0205474,
umls-concept:C0376358,
umls-concept:C0442805,
umls-concept:C0521117,
umls-concept:C1882417
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pubmed:issue |
10
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pubmed:dateCreated |
2011-4-6
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pubmed:abstractText |
Genetic polymorphisms that modify the detoxifying activity of glutathione S-transferases (GSTs) can affect the level of carcinogenic metabolites created by endogenous steroid hormones and exogenous chemical substances. Although the GSTM1 null genotype has been shown to increase prostate cancer mortality in Caucasians, potential associations between GST polymorphisms and prostate cancer biochemical recurrence (BCR) have not been well studied, particularly in African-Americans.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/19568698-10757075,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19568698-10813720,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19568698-11158191,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19568698-12436435,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19568698-12478126,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19568698-12597949,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19568698-12629352,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19568698-12817591,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19568698-15668493,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19568698-15822171,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19568698-15880531,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19568698-16173036,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19568698-16921513,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19568698-17067754,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19568698-17548691,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19568698-17558856,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19568698-17698101,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19568698-18242387,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19568698-18245535,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19568698-18287387,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19568698-18707696,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19568698-8619490,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19568698-8725388,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19568698-8885846
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1573-7225
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
20
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1915-26
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pubmed:dateRevised |
2011-7-28
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pubmed:meshHeading |
pubmed-meshheading:19568698-African Americans,
pubmed-meshheading:19568698-Aged,
pubmed-meshheading:19568698-Carcinoma,
pubmed-meshheading:19568698-Case-Control Studies,
pubmed-meshheading:19568698-Genetic Predisposition to Disease,
pubmed-meshheading:19568698-Glutathione S-Transferase pi,
pubmed-meshheading:19568698-Glutathione Transferase,
pubmed-meshheading:19568698-Humans,
pubmed-meshheading:19568698-Male,
pubmed-meshheading:19568698-Middle Aged,
pubmed-meshheading:19568698-Neoplasm Staging,
pubmed-meshheading:19568698-Polymorphism, Genetic,
pubmed-meshheading:19568698-Prostatic Neoplasms,
pubmed-meshheading:19568698-Recurrence,
pubmed-meshheading:19568698-Risk Factors,
pubmed-meshheading:19568698-Severity of Illness Index,
pubmed-meshheading:19568698-Tumor Markers, Biological
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pubmed:year |
2009
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pubmed:articleTitle |
Polymorphisms in glutathione S-transferase genes increase risk of prostate cancer biochemical recurrence differentially by ethnicity and disease severity.
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pubmed:affiliation |
Department of Epidemiology and Biostatistics, Case Western Reserve University, Cleveland, OH, USA. nln@case.edu
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, N.I.H., Extramural
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