rdf:type |
|
lifeskim:mentions |
umls-concept:C0010453,
umls-concept:C0017262,
umls-concept:C0019564,
umls-concept:C0022180,
umls-concept:C0034693,
umls-concept:C0034721,
umls-concept:C0037083,
umls-concept:C0185117,
umls-concept:C0242184,
umls-concept:C1519355,
umls-concept:C1519598,
umls-concept:C2911684
|
pubmed:issue |
2
|
pubmed:dateCreated |
2009-7-24
|
pubmed:abstractText |
Preconditioning neurons with noninjurious hypoxia (hypoxic preconditioning, HPC) or the anesthetic isoflurane (APC) induces tolerance of severe ischemic stress. The mechanisms of both types of preconditioning in the hippocampus require moderate increases in intracellular Ca and activation of protein kinase signaling. The authors hypothesized that the expression of signal transduction genes would be similar after APC and HPC.
|
pubmed:grant |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
AIM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Aug
|
pubmed:issn |
1528-1175
|
pubmed:author |
|
pubmed:issnType |
Electronic
|
pubmed:volume |
111
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
258-66
|
pubmed:meshHeading |
pubmed-meshheading:19568165-Anesthetics, Inhalation,
pubmed-meshheading:19568165-Animals,
pubmed-meshheading:19568165-Anoxia,
pubmed-meshheading:19568165-Blotting, Western,
pubmed-meshheading:19568165-Calcium,
pubmed-meshheading:19568165-Calcium Signaling,
pubmed-meshheading:19568165-Cell Death,
pubmed-meshheading:19568165-Glucose,
pubmed-meshheading:19568165-Hippocampus,
pubmed-meshheading:19568165-Isoflurane,
pubmed-meshheading:19568165-Nervous System Diseases,
pubmed-meshheading:19568165-Neurons,
pubmed-meshheading:19568165-Oligonucleotide Array Sequence Analysis,
pubmed-meshheading:19568165-Organ Culture Techniques,
pubmed-meshheading:19568165-Rats,
pubmed-meshheading:19568165-Rats, Sprague-Dawley,
pubmed-meshheading:19568165-Signal Transduction
|
pubmed:year |
2009
|
pubmed:articleTitle |
Expression of signal transduction genes differs after hypoxic or isoflurane preconditioning of rat hippocampal slice cultures.
|
pubmed:affiliation |
Department of Anesthesia and Perioperative Care, University of California, San Francisco, California 94143-0542, USA.
|
pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, N.I.H., Extramural
|