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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
2009-9-23
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pubmed:abstractText |
Increasing data support the hypothesis of a local and systemic crosstalk between adipocytes and monocytes mediated by fatty acids. The aim of this study was to characterize the immunomodulatory effects of a large panel of fatty acids on cytokines and chemokines in monocytic THP-1 cells and primary human monocytes. We tested whether anti-inflammatory fatty acids are able to inhibit the binding of lipopolysaccharide (LPS) to its receptor, toll-like receptor/MD-2 (TLR4/MD-2).
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1365-2362
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
39
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
924-33
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pubmed:meshHeading |
pubmed-meshheading:19563447-Adipocytes,
pubmed-meshheading:19563447-Blotting, Western,
pubmed-meshheading:19563447-Chemokine CCL2,
pubmed-meshheading:19563447-Diabetes Mellitus, Type 2,
pubmed-meshheading:19563447-Fatty Acids,
pubmed-meshheading:19563447-Female,
pubmed-meshheading:19563447-Humans,
pubmed-meshheading:19563447-Immunity, Innate,
pubmed-meshheading:19563447-Lipopolysaccharides,
pubmed-meshheading:19563447-Lymphocyte Antigen 96,
pubmed-meshheading:19563447-Male,
pubmed-meshheading:19563447-Middle Aged,
pubmed-meshheading:19563447-Monocytes,
pubmed-meshheading:19563447-Resistin,
pubmed-meshheading:19563447-Tumor Necrosis Factor-alpha
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pubmed:year |
2009
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pubmed:articleTitle |
Fatty acids as metabolic mediators in innate immunity.
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pubmed:affiliation |
Regensburg University Hospital, Regensburg, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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