Source:http://linkedlifedata.com/resource/pubmed/id/19562453
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7
|
pubmed:dateCreated |
2009-6-29
|
pubmed:abstractText |
Primary adenosquamous cell carcinomas (Ad-SCCs) of the colon and rectum are rare malignancies with a poor prognosis, in comparison to adenocarcinoma alone. Different roles of human papilloma virus (HPV) in its pathogenesis have been reported and the role of P16 in Ad-SCCs has not been explored. This report presents five cases of Ad-SCC of the colon to explore the clinicopathological features and the roles of P16, HPV 6/11, and 16/18. There was no confirmed evidence to support the relationship between the infection of HPV 6/11, 16/18, and pathogenesis of Ad-SCC of the colon. P16 overexpression was not related to HPV carcinogenesis and there might be another mechanism of P16 upregulation in Ad-SCC of the colon.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
1436-2813
|
pubmed:author | |
pubmed:issnType |
Electronic
|
pubmed:volume |
39
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
619-23
|
pubmed:meshHeading |
pubmed-meshheading:19562453-Adult,
pubmed-meshheading:19562453-Aged,
pubmed-meshheading:19562453-Alphapapillomavirus,
pubmed-meshheading:19562453-Carcinoma, Adenosquamous,
pubmed-meshheading:19562453-Colonic Neoplasms,
pubmed-meshheading:19562453-Female,
pubmed-meshheading:19562453-Human papillomavirus 11,
pubmed-meshheading:19562453-Human papillomavirus 16,
pubmed-meshheading:19562453-Human papillomavirus 18,
pubmed-meshheading:19562453-Human papillomavirus 6,
pubmed-meshheading:19562453-Humans,
pubmed-meshheading:19562453-Male,
pubmed-meshheading:19562453-Middle Aged,
pubmed-meshheading:19562453-Neoplasm Proteins,
pubmed-meshheading:19562453-Papillomavirus Infections,
pubmed-meshheading:19562453-Prognosis
|
pubmed:year |
2009
|
pubmed:articleTitle |
Primary adenosquamous carcinoma of the colon: report of five cases.
|
pubmed:affiliation |
Department of Anesthesiology, Medical School of Nanjing University, Nanjing Stomatology Hospital, Nanjing, PR China.
|
pubmed:publicationType |
Journal Article,
Case Reports,
Research Support, Non-U.S. Gov't
|