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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2010-5-7
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pubmed:abstractText |
Periodontitis is a chronic inflammatory disease, and genetic factors may have an important role in its severity. Polymorphisms in the promoter regions of the interleukin-6 (IL-6) and tumour necrosis factor-alpha (TNF-alpha) genes have been reported to cause changes in the production of these cytokines. The aim of this study was to evaluate the possible role of IL-6 (G-174C) and tumour necrosis factor (G-308A) polymorphisms, in the severity of chronic periodontitis in an elderly population.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
D
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1741-2358
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
27
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
70-5
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pubmed:meshHeading |
pubmed-meshheading:19555357-Adenine,
pubmed-meshheading:19555357-Aged,
pubmed-meshheading:19555357-Alleles,
pubmed-meshheading:19555357-Alveolar Bone Loss,
pubmed-meshheading:19555357-Chronic Periodontitis,
pubmed-meshheading:19555357-Cytosine,
pubmed-meshheading:19555357-Disease Progression,
pubmed-meshheading:19555357-Female,
pubmed-meshheading:19555357-Gene Frequency,
pubmed-meshheading:19555357-Genotype,
pubmed-meshheading:19555357-Gingival Hemorrhage,
pubmed-meshheading:19555357-Guanine,
pubmed-meshheading:19555357-Humans,
pubmed-meshheading:19555357-Interleukin-6,
pubmed-meshheading:19555357-Periodontal Attachment Loss,
pubmed-meshheading:19555357-Polymorphism, Genetic,
pubmed-meshheading:19555357-Promoter Regions, Genetic,
pubmed-meshheading:19555357-Tumor Necrosis Factor-alpha
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pubmed:year |
2010
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pubmed:articleTitle |
Interleukin-6 (G-174C) and tumour necrosis factor-alpha (G-308A) gene polymorphisms in geriatric patients with chronic periodontitis.
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pubmed:affiliation |
Restorative Dentistry Division, Catholic University of Brasília, Brasília, Brazil. anam@ucb.br
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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