Source:http://linkedlifedata.com/resource/pubmed/id/19551732
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
2009-6-29
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pubmed:abstractText |
The MeOH extract and its BuOH-soluble fraction (crude saponin fraction) from the flower buds of Chinese tea plant (Camellia sinensis (L.) O. KUNTZE; Fujian Province) were found to exhibit accelerating effects on gastrointestinal transit in mice and inhibitory effects against pancreatic lipase. From the BuOH-soluble fraction, three new acylated oleanane-type triterpene oligoglycosides, chakasaponins I, II, and III (1-3, resp.), were isolated together with 13 known compounds. The chemical structures 1-3 were elucidated on the basis of chemical and physicochemical evidence. Compounds 1-3 showed accelerating effects on gastrointestinal transit in mice and inhibitory effects against porcine pancreatic lipase (IC(50)=150-530 microM).
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Lipase,
http://linkedlifedata.com/resource/pubmed/chemical/Oleanolic Acid,
http://linkedlifedata.com/resource/pubmed/chemical/Plant Extracts,
http://linkedlifedata.com/resource/pubmed/chemical/Saponins,
http://linkedlifedata.com/resource/pubmed/chemical/Tea,
http://linkedlifedata.com/resource/pubmed/chemical/Triterpenes,
http://linkedlifedata.com/resource/pubmed/chemical/oleanane
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1612-1880
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
6
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
903-15
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pubmed:meshHeading |
pubmed-meshheading:19551732-Acylation,
pubmed-meshheading:19551732-Animals,
pubmed-meshheading:19551732-Camellia sinensis,
pubmed-meshheading:19551732-Flowers,
pubmed-meshheading:19551732-Gastrointestinal Transit,
pubmed-meshheading:19551732-Lipase,
pubmed-meshheading:19551732-Male,
pubmed-meshheading:19551732-Mice,
pubmed-meshheading:19551732-Oleanolic Acid,
pubmed-meshheading:19551732-Plant Extracts,
pubmed-meshheading:19551732-Saponins,
pubmed-meshheading:19551732-Tea,
pubmed-meshheading:19551732-Triterpenes
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pubmed:year |
2009
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pubmed:articleTitle |
Acylated oleanane-type triterpene saponins with acceleration of gastrointestinal transit and inhibitory effect on pancreatic lipase from flower buds of chinese tea plant (Camellia sinensis).
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pubmed:affiliation |
Kyoto Pharmaceutical University, Misasagi, Yamashina-ku, Kyoto 607-8412, Japan. myoshika@mb.kyoto-phu.ac.jp
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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