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PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2009-6-29
pubmed:abstractText
The MeOH extract and its BuOH-soluble fraction (crude saponin fraction) from the flower buds of Chinese tea plant (Camellia sinensis (L.) O. KUNTZE; Fujian Province) were found to exhibit accelerating effects on gastrointestinal transit in mice and inhibitory effects against pancreatic lipase. From the BuOH-soluble fraction, three new acylated oleanane-type triterpene oligoglycosides, chakasaponins I, II, and III (1-3, resp.), were isolated together with 13 known compounds. The chemical structures 1-3 were elucidated on the basis of chemical and physicochemical evidence. Compounds 1-3 showed accelerating effects on gastrointestinal transit in mice and inhibitory effects against porcine pancreatic lipase (IC(50)=150-530 microM).
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
1612-1880
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
6
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
903-15
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Acylated oleanane-type triterpene saponins with acceleration of gastrointestinal transit and inhibitory effect on pancreatic lipase from flower buds of chinese tea plant (Camellia sinensis).
pubmed:affiliation
Kyoto Pharmaceutical University, Misasagi, Yamashina-ku, Kyoto 607-8412, Japan. myoshika@mb.kyoto-phu.ac.jp
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't