|
pubmed:abstractText |
Numerous preclinical studies have shown that local photodynamic therapy (PDT) of tumors enhances systemic antitumor immunity. However, other than single-case and anecdotal reports, this phenomenon has not been examined following clinical PDT. To determine whether PDT in a clinical setting enhances systemic recognition of tumor cells, we examined whether PDT of basal cell carcinoma resulted in an increased systemic immune response to Hip1, a tumor antigen associated with basal cell carcinoma.
|
|
pubmed:affiliation |
Authors' Affiliations: PDT Center, Department of Cell Stress Biology, Department of Dermatology, Department of Biostatistics, Roswell Park Cancer Center, Buffalo, New York.
|
