Linked Life Data

19549748

Source:http://linkedlifedata.com/resource/pubmed/id/19549748

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2009-8-24
pubmed:abstractText
Evidence from long-term clinical studies measuring urinary steroid ratios, and from in vitro studies, suggests that GH administered for longer than 2 months down-regulates 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1), thereby reducing cortisol regeneration in liver and adipose tissue. We aimed to measure acute effects of GH on 11beta-HSD1 in liver and adipose tissue in vivo, including using a stable isotope tracer.
pubmed:grant
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/19549748-10566668, http://linkedlifedata.com/resource/pubmed/commentcorrection/19549748-10770221, http://linkedlifedata.com/resource/pubmed/commentcorrection/19549748-11316764, http://linkedlifedata.com/resource/pubmed/commentcorrection/19549748-11443156, http://linkedlifedata.com/resource/pubmed/commentcorrection/19549748-11788660, http://linkedlifedata.com/resource/pubmed/commentcorrection/19549748-12727963, http://linkedlifedata.com/resource/pubmed/commentcorrection/19549748-14616886, http://linkedlifedata.com/resource/pubmed/commentcorrection/19549748-15004437, http://linkedlifedata.com/resource/pubmed/commentcorrection/19549748-15531488, http://linkedlifedata.com/resource/pubmed/commentcorrection/19549748-15855321, http://linkedlifedata.com/resource/pubmed/commentcorrection/19549748-16368752, http://linkedlifedata.com/resource/pubmed/commentcorrection/19549748-16381993, http://linkedlifedata.com/resource/pubmed/commentcorrection/19549748-17327378, http://linkedlifedata.com/resource/pubmed/commentcorrection/19549748-17371460, http://linkedlifedata.com/resource/pubmed/commentcorrection/19549748-7828353, http://linkedlifedata.com/resource/pubmed/commentcorrection/19549748-9302399, http://linkedlifedata.com/resource/pubmed/commentcorrection/19549748-9322500, http://linkedlifedata.com/resource/pubmed/commentcorrection/19549748-9496245, http://linkedlifedata.com/resource/pubmed/commentcorrection/19549748-9579226, http://linkedlifedata.com/resource/pubmed/commentcorrection/19549748-9828916
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
1479-683X
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
161
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
375-80
pubmed:dateRevised
2010-9-24
pubmed:meshHeading
pubmed-meshheading:19549748-11-beta-Hydroxysteroid Dehydrogenase Type 1, pubmed-meshheading:19549748-Adipose Tissue, White, pubmed-meshheading:19549748-Adult, pubmed-meshheading:19549748-Aged, pubmed-meshheading:19549748-Drug Dosage Calculations, pubmed-meshheading:19549748-Gene Expression Regulation, Enzymologic, pubmed-meshheading:19549748-Glucocorticoids, pubmed-meshheading:19549748-Hormone Replacement Therapy, pubmed-meshheading:19549748-Human Growth Hormone, pubmed-meshheading:19549748-Humans, pubmed-meshheading:19549748-Hydrocortisone, pubmed-meshheading:19549748-Hypopituitarism, pubmed-meshheading:19549748-Male, pubmed-meshheading:19549748-Middle Aged, pubmed-meshheading:19549748-Placebos, pubmed-meshheading:19549748-Time Factors, pubmed-meshheading:19549748-Withholding Treatment, pubmed-meshheading:19549748-Young Adult
pubmed:year
2009
pubmed:articleTitle
Lack of regulation of 11beta-hydroxysteroid dehydrogenase type 1 during short-term manipulation of GH in patients with hypopituitarism.
pubmed:affiliation
Department of Endocrinology and Metabolism, Sahlgrenska Academy, Gothenburg University, Sahlgrenska University Hospital, Gröna stråket 8, 413 45 Göteborg, Sweden. helga.sigurjonsdottir@gu.se
pubmed:publicationType
Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't