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pubmed-article:19545435pubmed:abstractTextIn streptozotocin-injected rats (STZ-rats), we previously demonstrated a role for angiotensin II (AT-II) in cardiac remodelling and insulin resistance partially counteracted by in vivo treatment with losartan, an AT-II receptor antagonist.We now aimed to investigate the effect of treating diabetic STZ-rats with losartan on diabetes vascular response to vasoconstrictors.lld:pubmed
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pubmed-article:19545435pubmed:articleTitleLosartan counteracts the hyper-reactivity to angiotensin II and ROCK1 over-activation in aortas isolated from streptozotocin-injected diabetic rats.lld:pubmed
pubmed-article:19545435pubmed:affiliationDept. of Pharmacology, University of Florence, Viale G, Pieraccini 6, Florence, Italy. paola.failli@unifi.itlld:pubmed
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