Linked Life Data

1954516

Source:http://linkedlifedata.com/resource/pubmed/id/1954516

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
1991-12-30
pubmed:abstractText
In rabbits, skin wounds were expanded by inflation of a subcutaneously implanted tissue expander in order to study the effect of mechanical stress on wound healing. Biomechanical and histomorphological properties of both expanded and non-expanded control wounds were evaluated. Expanded wounds demonstrated a significant increase in maximum load (80%) and energy absorption at maximum load (95%), when compared to non-expanded control wounds. Histomorphologically, the expanded wounds were stretched in comparison to the control wounds. The collagen in expanded wounds showed an orientation parallel to the direction of force, and displayed a more organised configuration. It is concluded that the use of tissue expanders permits the standardisation of the mechanical stress applied to experimental skin wounds. It is found that mechanical stress accelerates wound healing by producing stronger and more organised scars, however, at the expense of scar stretching.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0007-1226
pubmed:author
pubmed:issnType
Print
pubmed:volume
44
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
514-9
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
The effect of mechanical stress on healing skin wounds: an experimental study in rabbits using tissue expansion.
pubmed:affiliation
Department of Surgical Research, University of Amsterdam, The Netherlands.
pubmed:publicationType
Journal Article