Source:http://linkedlifedata.com/resource/pubmed/id/19542552
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
25
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pubmed:dateCreated |
2009-6-22
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pubmed:abstractText |
Forty-four dogs naturally infected by Leishmania infantum were divided into two groups: 20 thrombocytopenic dogs with fewer than 150 x 10(9) platelets/l, and 24 non-thrombocytopenic dogs with more than 200 x 10(9) platelets/l. Ten clinically healthy dogs were used as controls. A haematological profile was obtained and the dogs' serum was used to assess the presence of platelet-binding IgM and IgG antibodies using a flow cytometry technique. Nineteen of the 20 thrombocytopenic dogs, and 13 of the 24 non-thrombocytopenic dogs had detectable levels of platelet-binding immunoglobulins, but none of the control dogs did so. The differences were significantly different for both IgM and IgG platelet-binding antibodies.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0042-4900
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
20
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pubmed:volume |
164
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
778-82
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pubmed:meshHeading |
pubmed-meshheading:19542552-Animals,
pubmed-meshheading:19542552-Antibodies, Protozoan,
pubmed-meshheading:19542552-Blood Platelets,
pubmed-meshheading:19542552-Dog Diseases,
pubmed-meshheading:19542552-Dogs,
pubmed-meshheading:19542552-Female,
pubmed-meshheading:19542552-Flow Cytometry,
pubmed-meshheading:19542552-Fluorescence,
pubmed-meshheading:19542552-Immunoglobulin G,
pubmed-meshheading:19542552-Immunoglobulin M,
pubmed-meshheading:19542552-Leishmania infantum,
pubmed-meshheading:19542552-Leishmaniasis, Visceral,
pubmed-meshheading:19542552-Male,
pubmed-meshheading:19542552-Purpura, Thrombocytopenic, Idiopathic
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pubmed:year |
2009
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pubmed:articleTitle |
Secondary immune-mediated thrombocytopenia in dogs naturally infected by Leishmania infantum.
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pubmed:affiliation |
Department of Veterinary Clinical Sciences, Internal Medicine Section, University of Naples Federico II, Via Delpino, Italy. lcortese@unina.it
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pubmed:publicationType |
Journal Article
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