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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
11
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pubmed:dateCreated |
2009-12-24
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pubmed:abstractText |
Symptoms of somatoform and affective disorders are thought to be connected to serotonergic neurotransmission because serotonin is known to regulate the functions relevant in these disorders, such as pain and mood. Previous studies have reported associations of these disorders with a functional polymorphism in the promoter region of the serotonin transporter gene, a limiting factor of the serotonergic neuronal system, as its alleles have been associated with differences in levels of synthesized transporter and therefore differences in reuptake efficiency.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1555-2101
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pubmed:author |
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pubmed:copyrightInfo |
Copyright 2009 Physicians Postgraduate Press, Inc.
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pubmed:issnType |
Electronic
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pubmed:volume |
70
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1536-9
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pubmed:meshHeading |
pubmed-meshheading:19538902-Checklist,
pubmed-meshheading:19538902-Depressive Disorder, Major,
pubmed-meshheading:19538902-Diagnostic and Statistical Manual of Mental Disorders,
pubmed-meshheading:19538902-Female,
pubmed-meshheading:19538902-Gene Expression,
pubmed-meshheading:19538902-Gene Frequency,
pubmed-meshheading:19538902-Genetic Variation,
pubmed-meshheading:19538902-Genotype,
pubmed-meshheading:19538902-Humans,
pubmed-meshheading:19538902-International Classification of Diseases,
pubmed-meshheading:19538902-Male,
pubmed-meshheading:19538902-Middle Aged,
pubmed-meshheading:19538902-Personality Inventory,
pubmed-meshheading:19538902-Polymorphism, Genetic,
pubmed-meshheading:19538902-Promoter Regions, Genetic,
pubmed-meshheading:19538902-Psychiatric Status Rating Scales,
pubmed-meshheading:19538902-Serotonin Plasma Membrane Transport Proteins,
pubmed-meshheading:19538902-Somatoform Disorders
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pubmed:year |
2009
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pubmed:articleTitle |
Serotonin transporter gene promoter polymorphism and somatoform symptoms.
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pubmed:affiliation |
Division of Clinical Psychology and Psychotherapy, Philipps University of Marburg, Gutenbergstrasse 18, 35032 Marburg, Germany. anika.hennings@staff.uni-marburg.de
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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