|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0004083,
umls-concept:C0023467,
umls-concept:C0034897,
umls-concept:C0035647,
umls-concept:C0085669,
umls-concept:C0238598,
umls-concept:C0332281,
umls-concept:C0596611,
umls-concept:C0694898,
umls-concept:C1556084,
umls-concept:C2603343
|
|
pubmed:issue |
16
|
|
pubmed:dateCreated |
2009-8-11
|
|
pubmed:abstractText |
Wilms tumor 1 (WT1) is a transcription factor that is overexpressed in most acute myeloid leukemias (AMLs). Recently, 2 groups reported that WT1 mutations occur in approximately 10% of normal karyotype AMLs and are an independent predictor of poor outcome in this subgroup of patients with AML.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
AIM
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Aug
|
|
pubmed:issn |
0008-543X
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:day |
15
|
|
pubmed:volume |
115
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
3719-27
|
|
pubmed:meshHeading |
pubmed-meshheading:19536888-Adolescent,
pubmed-meshheading:19536888-Adult,
pubmed-meshheading:19536888-Female,
pubmed-meshheading:19536888-Genes, Wilms Tumor,
pubmed-meshheading:19536888-Humans,
pubmed-meshheading:19536888-Leukemia, Myeloid, Acute,
pubmed-meshheading:19536888-Male,
pubmed-meshheading:19536888-Middle Aged,
pubmed-meshheading:19536888-Mutation,
pubmed-meshheading:19536888-Prognosis,
pubmed-meshheading:19536888-Recurrence,
pubmed-meshheading:19536888-Retrospective Studies,
pubmed-meshheading:19536888-Young Adult
|
|
pubmed:year |
2009
|
|
pubmed:articleTitle |
Wilms tumor 1 gene mutations are associated with a higher risk of recurrence in young adults with acute myeloid leukemia: a study from the Acute Leukemia French Association.
|
|
pubmed:affiliation |
Department of Hematology, University of Lille Medical School, Lille, France.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
