Linked Life Data

19535899

Source:http://linkedlifedata.com/resource/pubmed/id/19535899

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2009-7-20
pubmed:abstractText
DNA methylation is an important epigenetic mark that is involved in the regulation of many cellular processes such as gene expression, genomic imprinting and silencing of repetitive elements. Because of their ability to cause and capture phenotypic plasticity, epigenetic marks such as DNA methylation represent potential biomarkers to distinguish between different types of tissues and stages of differentiation. Here, we have identified differential DNA methylation in the gene body of the nitric oxide inhibitor Ddah2 that discriminates embryonic stem cells from neural stem cells and is positively correlated with differential gene expression.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
1559-2308
pubmed:author
pubmed:issnType
Electronic
pubmed:day
16
pubmed:volume
4
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
248-54
pubmed:dateRevised
2010-8-6
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Gene body methylation of the dimethylarginine dimethylamino-hydrolase 2 (Ddah2) gene is an epigenetic biomarker for neural stem cell differentiation.
pubmed:affiliation
UCL Cancer Institute, University College London, London WC1E 6BT, UK. l.backdahl@ucl.ac.uk
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't