Linked Life Data

19531846

Source:http://linkedlifedata.com/resource/pubmed/id/19531846

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
13
pubmed:dateCreated
2009-6-22
pubmed:abstractText
Sub-harmonic imaging using encapsulated microbubbles (EMs) improves the contrast of ultrasound imaging by taking advantage of increased contrast to the tissue signal. A dual-frequency excitation technique (DFET) is proposed for enhancing the sub-harmonic emission from EMs as compared with the conventional single frequency sinusoidal excitation technique (SFSET). This study includes theoretical simulation and in vitro experimental verification. A dual-frequency signal (2 and 4 MHz) is used to insonate EMs developed in our laboratory. Both theoretical and experimental studies indicate that the DFET may be able to improve the amplitude of the sub-harmonic component up to 13 dB over the SFSET. Increasing the value of the pulse repetition frequency or the number of cycles of ultrasound tone burst in the application of the DFET may increase the sub-harmonic emission. Furthermore, it is confirmed that the amplitude ratio of the second frequency (4 MHz) to the first frequency (2 MHz) and phase shift of the second frequency with respect to the first frequency also play an important role in sub-harmonic emission. A ratio of 0.5 and a phase shift around 180 degrees are found to be the optimum values.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0031-9155
pubmed:author
pubmed:issnType
Print
pubmed:day
7
pubmed:volume
54
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
4257-72
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
A dual-frequency excitation technique for enhancing the sub-harmonic emission from encapsulated microbubbles.
pubmed:affiliation
Institute of Acoustics, Key Laboratory of Modern Acoustics (Nanjing University), Ministry of Education, Nanjing University, Nanjing, People's Republic of China. dzhang@nju.edu.cn
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't