Linked Life Data

19530714

Source:http://linkedlifedata.com/resource/pubmed/id/19530714

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
2009-6-17
pubmed:abstractText
An analytical method incorporating simple liquid extraction followed by mixed mode cation exchange/reversed phase solid phase extraction and liquid chromatography-tandem mass spectrometry was developed and validated for the analysis of melamine (MEL) in liquid and powdered infant formula. The method used two different MEL stable isotope labeled internal standards to monitor analyte recoveries and to account for matrix effects. The method is sensitive (limit of quantitation of 4 ng/g), accurate, and precise (during validation, recoveries corrected by internal recovery standard averaged between 92 and 104% for all fortification levels and matrices). The method was used to analyze 94 samples of infant formula purchased from major retailers in Ottawa, ON, Canada, to examine whether or not Canadian infants are exposed to background levels of MEL. MEL was detected in 71 of the 94 products analyzed at concentrations ranging from 4.31 to 346 ng/g (median = 16 ng/g). A comparison of estimated dietary exposures to the recently recommended World Health Organization toxicological reference value for melamine suggests that the presence of low levels of MEL in infant formula purchased in Canada does not represent a health risk.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
1520-5118
pubmed:author
pubmed:issnType
Electronic
pubmed:day
24
pubmed:volume
57
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
5340-4
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Melamine in infant formula sold in Canada: occurrence and risk assessment.
pubmed:affiliation
Food Research Division, Banting Research Centre 2203D, Health Canada, Ottawa, Ontario, Canada. sheryl_tittlemier@hc-sc.gc.ca
pubmed:publicationType
Journal Article, Evaluation Studies