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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2009-6-16
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pubmed:abstractText |
The escape mechanisms leading to trastuzumab-resistance are under investigation, but no report has yet described the mechanisms of escape from trastuzumab-mediated antibody-dependent cellular cytotoxicity (ADCC). In the present study, the mechanisms of escape from trastuzumab-mediated ADCC were elucidated using esophageal squamous cell carcinoma (SCC) cell clones.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Monoclonal,
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Monoclonal, Humanized,
http://linkedlifedata.com/resource/pubmed/chemical/Antineoplastic Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Granzymes,
http://linkedlifedata.com/resource/pubmed/chemical/Perforin,
http://linkedlifedata.com/resource/pubmed/chemical/Receptor, erbB-2,
http://linkedlifedata.com/resource/pubmed/chemical/trastuzumab
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0250-7005
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
29
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2137-46
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:19528474-Antibodies, Monoclonal,
pubmed-meshheading:19528474-Antibodies, Monoclonal, Humanized,
pubmed-meshheading:19528474-Antibody-Dependent Cell Cytotoxicity,
pubmed-meshheading:19528474-Antineoplastic Agents,
pubmed-meshheading:19528474-Apoptosis,
pubmed-meshheading:19528474-Carcinoma, Squamous Cell,
pubmed-meshheading:19528474-Cell Line, Tumor,
pubmed-meshheading:19528474-Cell Proliferation,
pubmed-meshheading:19528474-Esophageal Neoplasms,
pubmed-meshheading:19528474-Flow Cytometry,
pubmed-meshheading:19528474-Granzymes,
pubmed-meshheading:19528474-Humans,
pubmed-meshheading:19528474-Killer Cells, Natural,
pubmed-meshheading:19528474-Perforin,
pubmed-meshheading:19528474-Receptor, erbB-2
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pubmed:year |
2009
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pubmed:articleTitle |
Mechanisms of escape from trastuzumab-mediated ADCC in esophageal squamous cell carcinoma: relation to susceptibility to perforin-granzyme.
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pubmed:affiliation |
First Department of Surgery, University of Yamanashi, Chuo-city, Yamanashi 409-3898, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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