Linked Life Data

19525448

Source:http://linkedlifedata.com/resource/pubmed/id/19525448

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
2009-8-4
pubmed:abstractText
Chemokine receptor 4 (CXCR4) is expressed in a variety of cancers, including breast, brain, ovarian, and prostate. CXCR4-CXCL12 interactions are critical for tumor development, growth, and metastasis. Compared with normal tissue, neoplastic tissue (including metastases) expresses high levels of CXCR4. Previous clinical and preclinical observations suggest that CXCR4 levels could be used as a predictive marker of metastatic potential. Here we report the results of SPECT/CT of CXCR4 expression levels in experimental brain tumors using (125)I-labeled anti-CXCR4 monoclonal antibodies (mAbs).
pubmed:grant
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/19525448-10452968, http://linkedlifedata.com/resource/pubmed/commentcorrection/19525448-10656438, http://linkedlifedata.com/resource/pubmed/commentcorrection/19525448-10699287, http://linkedlifedata.com/resource/pubmed/commentcorrection/19525448-11533159, http://linkedlifedata.com/resource/pubmed/commentcorrection/19525448-12690099, http://linkedlifedata.com/resource/pubmed/commentcorrection/19525448-12761880, http://linkedlifedata.com/resource/pubmed/commentcorrection/19525448-12796357, http://linkedlifedata.com/resource/pubmed/commentcorrection/19525448-12892230, http://linkedlifedata.com/resource/pubmed/commentcorrection/19525448-12927045, http://linkedlifedata.com/resource/pubmed/commentcorrection/19525448-14595012, http://linkedlifedata.com/resource/pubmed/commentcorrection/19525448-14597738, http://linkedlifedata.com/resource/pubmed/commentcorrection/19525448-15650218, http://linkedlifedata.com/resource/pubmed/commentcorrection/19525448-15987467, http://linkedlifedata.com/resource/pubmed/commentcorrection/19525448-16168141, http://linkedlifedata.com/resource/pubmed/commentcorrection/19525448-16344916, http://linkedlifedata.com/resource/pubmed/commentcorrection/19525448-16407848, http://linkedlifedata.com/resource/pubmed/commentcorrection/19525448-16489086, http://linkedlifedata.com/resource/pubmed/commentcorrection/19525448-16682724, http://linkedlifedata.com/resource/pubmed/commentcorrection/19525448-16720240, http://linkedlifedata.com/resource/pubmed/commentcorrection/19525448-17075581, http://linkedlifedata.com/resource/pubmed/commentcorrection/19525448-17121897, http://linkedlifedata.com/resource/pubmed/commentcorrection/19525448-1732052, http://linkedlifedata.com/resource/pubmed/commentcorrection/19525448-17333178, http://linkedlifedata.com/resource/pubmed/commentcorrection/19525448-17763975, http://linkedlifedata.com/resource/pubmed/commentcorrection/19525448-17881971, http://linkedlifedata.com/resource/pubmed/commentcorrection/19525448-19088012, http://linkedlifedata.com/resource/pubmed/commentcorrection/19525448-19091888, http://linkedlifedata.com/resource/pubmed/commentcorrection/19525448-2297731, http://linkedlifedata.com/resource/pubmed/commentcorrection/19525448-2297732, http://linkedlifedata.com/resource/pubmed/commentcorrection/19525448-2297733, http://linkedlifedata.com/resource/pubmed/commentcorrection/19525448-2469537, http://linkedlifedata.com/resource/pubmed/commentcorrection/19525448-3262228, http://linkedlifedata.com/resource/pubmed/commentcorrection/19525448-6086763, http://linkedlifedata.com/resource/pubmed/commentcorrection/19525448-8995702, http://linkedlifedata.com/resource/pubmed/commentcorrection/19525448-9808513
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0161-5505
pubmed:author
pubmed:issnType
Print
pubmed:volume
50
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1124-30
pubmed:dateRevised
2011-7-28
pubmed:meshHeading
pubmed-meshheading:19525448-Animals, pubmed-meshheading:19525448-Antibodies, Monoclonal, pubmed-meshheading:19525448-Brain Neoplasms, pubmed-meshheading:19525448-Cell Line, Tumor, pubmed-meshheading:19525448-Gene Expression Profiling, pubmed-meshheading:19525448-Glioblastoma, pubmed-meshheading:19525448-Immunoassay, pubmed-meshheading:19525448-Iodine Radioisotopes, pubmed-meshheading:19525448-Male, pubmed-meshheading:19525448-Mice, pubmed-meshheading:19525448-Mice, Inbred BALB C, pubmed-meshheading:19525448-Mice, SCID, pubmed-meshheading:19525448-Molecular Probe Techniques, pubmed-meshheading:19525448-Neoplasm Proteins, pubmed-meshheading:19525448-Radiopharmaceuticals, pubmed-meshheading:19525448-Receptors, CXCR4, pubmed-meshheading:19525448-Subtraction Technique, pubmed-meshheading:19525448-Tissue Distribution, pubmed-meshheading:19525448-Tomography, Emission-Computed, Single-Photon, pubmed-meshheading:19525448-Tomography, X-Ray Computed, pubmed-meshheading:19525448-Tumor Markers, Biological
pubmed:year
2009
pubmed:articleTitle
Immunoimaging of CXCR4 expression in brain tumor xenografts using SPECT/CT.
pubmed:affiliation
Russell H. Morgan Department of Radiology and Radiological Sciences, Johns Hopkins University, Baltimore, Maryland, USA.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural