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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2009-7-1
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pubmed:databankReference |
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pubmed:abstractText |
The multi-arm multi-stage (MAMS) trial is a new paradigm for conducting randomised controlled trials that allows the simultaneous assessment of a number of research treatments against a single control arm. MAMS trials provide earlier answers and are potentially more cost-effective than a series of traditionally designed trials. Prostate cancer is the most common tumour in men and there is a need to improve outcomes for men with hormone-sensitive, advanced disease as quickly as possible. The MAMS design will potentially facilitate evaluation and testing of new therapies in this and other diseases.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/19519885-11308265,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19519885-12351594,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19519885-12854091,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19519885-15201755,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19519885-15470213,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19519885-15470214,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19519885-15721478,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19519885-16225513,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19519885-16278665,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19519885-16730974,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19519885-16750497,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19519885-16972715,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19519885-17105795,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19519885-17630037,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19519885-18024867,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19519885-18226741,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19519885-18226746,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19519885-18421050,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19519885-18728279,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19519885-18760574,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19519885-18990168,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19519885-19002178,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19519885-19091394,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19519885-2727467,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19519885-7661937,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19519885-9761805
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1745-6215
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
39
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:19519885-Androgen Antagonists,
pubmed-meshheading:19519885-Antineoplastic Agents,
pubmed-meshheading:19519885-Data Interpretation, Statistical,
pubmed-meshheading:19519885-Diphosphonates,
pubmed-meshheading:19519885-Drug Therapy, Combination,
pubmed-meshheading:19519885-Humans,
pubmed-meshheading:19519885-Imidazoles,
pubmed-meshheading:19519885-Male,
pubmed-meshheading:19519885-Prostatic Neoplasms,
pubmed-meshheading:19519885-Randomized Controlled Trials as Topic,
pubmed-meshheading:19519885-Software,
pubmed-meshheading:19519885-Taxoids
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pubmed:year |
2009
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pubmed:articleTitle |
Issues in applying multi-arm multi-stage methodology to a clinical trial in prostate cancer: the MRC STAMPEDE trial.
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pubmed:affiliation |
MRC Clinical Trials Unit, London, UK. matthew.sydes@ctu.mrc.ac.uk
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pubmed:publicationType |
Journal Article,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't,
Multicenter Study
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