rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
10
|
pubmed:dateCreated |
2009-9-24
|
pubmed:abstractText |
Previous studies indicate that the Wnt/beta-catenin-signaling pathway is active and functional during murine lens development. In this study, the consequences of constitutively activating the pathway in lens during development were investigated.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
|
pubmed:issn |
1552-5783
|
pubmed:author |
|
pubmed:issnType |
Electronic
|
pubmed:volume |
50
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
4794-806
|
pubmed:meshHeading |
pubmed-meshheading:19515997-Adenomatous Polyposis Coli Protein,
pubmed-meshheading:19515997-Animals,
pubmed-meshheading:19515997-Apoptosis,
pubmed-meshheading:19515997-Bromodeoxyuridine,
pubmed-meshheading:19515997-Cell Cycle Proteins,
pubmed-meshheading:19515997-Cell Differentiation,
pubmed-meshheading:19515997-Cell Proliferation,
pubmed-meshheading:19515997-Epithelial Cells,
pubmed-meshheading:19515997-Female,
pubmed-meshheading:19515997-Fluorescent Antibody Technique, Indirect,
pubmed-meshheading:19515997-Frameshift Mutation,
pubmed-meshheading:19515997-In Situ Nick-End Labeling,
pubmed-meshheading:19515997-Lens, Crystalline,
pubmed-meshheading:19515997-Male,
pubmed-meshheading:19515997-Mice,
pubmed-meshheading:19515997-Mice, Transgenic,
pubmed-meshheading:19515997-Phenotype,
pubmed-meshheading:19515997-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:19515997-Signal Transduction,
pubmed-meshheading:19515997-Wnt Proteins,
pubmed-meshheading:19515997-beta Catenin
|
pubmed:year |
2009
|
pubmed:articleTitle |
Conditional mutations of beta-catenin and APC reveal roles for canonical Wnt signaling in lens differentiation.
|
pubmed:affiliation |
Ocular Development Laboratory, Department of Anatomy and Cell Biology, University of Melbourne, Victoria, Australia.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|