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pubmed-article:19514858pubmed:abstractTextThe fetal inflammatory response syndrome (FIRS) is present in a fraction of fetuses exposed to intra-amniotic infection and is associated with the impending onset of labor and multisystem organ involvement. Neonates born with funisitis, the histologic counterpart of fetal systemic inflammation, are at increased risk for cerebral palsy and bronchopulmonary dysplasia. The aim of this study was to determine whether fetal and maternal granulocytes and monocytes have the phenotypic and metabolic characteristics of activation in cases with FIRS.lld:pubmed
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pubmed-article:19514858pubmed:articleTitleEvidence of changes in the immunophenotype and metabolic characteristics (intracellular reactive oxygen radicals) of fetal, but not maternal, monocytes and granulocytes in the fetal inflammatory response syndrome.lld:pubmed
pubmed-article:19514858pubmed:affiliationPerinatology Research Branch, NICHD, NIH, DHHS, Wayne State University/Hutzel Women's Hospital, Detroit, MI 48201, USA.lld:pubmed
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pubmed-article:19514858pubmed:publicationTypeResearch Support, N.I.H., Intramurallld:pubmed
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