|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
6
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|
pubmed:dateCreated |
2009-6-9
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|
pubmed:abstractText |
A finite number of variants in the OPRM1, COMT, MC1R, ABCB1 and CYP2D6 genes has been identified to significantly modulate the effects of opioids in controlled homogenous settings. We analyzed the imprint of these variants in opioid therapy in a highly variable cohort of pain patients treated in outpatient units to test whether genotyping may play a role in this clinical setting.
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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|
pubmed:month |
Jun
|
|
pubmed:issn |
1744-6872
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|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
19
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
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|
pubmed:pagination |
429-36
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pubmed:meshHeading |
pubmed-meshheading:19514130-Aged,
pubmed-meshheading:19514130-Ambulatory Care,
pubmed-meshheading:19514130-Analgesics, Opioid,
pubmed-meshheading:19514130-Cohort Studies,
pubmed-meshheading:19514130-Cross-Sectional Studies,
pubmed-meshheading:19514130-Female,
pubmed-meshheading:19514130-Genotype,
pubmed-meshheading:19514130-Humans,
pubmed-meshheading:19514130-Male,
pubmed-meshheading:19514130-Middle Aged,
pubmed-meshheading:19514130-P-Glycoprotein,
pubmed-meshheading:19514130-Pain,
pubmed-meshheading:19514130-Pain Clinics,
pubmed-meshheading:19514130-Receptors, Opioid, mu
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|
pubmed:year |
2009
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|
pubmed:articleTitle |
Cross-sectional analysis of the influence of currently known pharmacogenetic modulators on opioid therapy in outpatient pain centers.
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pubmed:affiliation |
pharmazentrum frankfurt/ZAFES, Institute of Clinical Pharmacology, Johann Wolfgang Goethe-University, Frankfurt am Main, Germany. j.loetsch@em.uni-frankfurt.de
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, Non-U.S. Gov't,
Multicenter Study
|
