Source:http://linkedlifedata.com/resource/pubmed/id/19508991
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2009-8-31
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pubmed:abstractText |
To estimate the annualized rate of progression of vessel-wall volume in the carotid arteries in 160 patients by using magnetic resonance (MR) imaging and to establish the fraction of studies that have acceptable image quality. Materials and Methods: The study procedures and consent forms were reviewed and approved by each site's institutional review board. All U.S. study sites conducted all phases of this study in compliance with HIPAA requirements. Written consent was obtained from each participant. One hundred sixty patients with greater than 50% narrowing of the diameter of the carotid artery were recruited at six centers for prospective imaging of the carotid arteries at baseline and 1 year later by using high-spatial-resolution, 1.5-T MR imaging. Studies with unacceptable image quality were excluded. Quantitative changes in atheroma volume were measured on unenhanced T1-weighted images. A multiple linear regression analysis was used to correlate progression with several clinical factors, including statin therapy.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1527-1315
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
252
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
789-96
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pubmed:dateRevised |
2010-9-2
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pubmed:meshHeading |
pubmed-meshheading:19508991-Atherosclerosis,
pubmed-meshheading:19508991-Carotid Artery Diseases,
pubmed-meshheading:19508991-Chi-Square Distribution,
pubmed-meshheading:19508991-Disease Progression,
pubmed-meshheading:19508991-Female,
pubmed-meshheading:19508991-Humans,
pubmed-meshheading:19508991-Hydroxymethylglutaryl-CoA Reductase Inhibitors,
pubmed-meshheading:19508991-Image Enhancement,
pubmed-meshheading:19508991-Linear Models,
pubmed-meshheading:19508991-Magnetic Resonance Imaging,
pubmed-meshheading:19508991-Male,
pubmed-meshheading:19508991-Reproducibility of Results,
pubmed-meshheading:19508991-United States
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pubmed:year |
2009
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pubmed:articleTitle |
Atherosclerotic plaque progression in carotid arteries: monitoring with high-spatial-resolution MR imaging--multicenter trial.
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pubmed:affiliation |
Department of Radiology, University of California, San Francisco, San Francisco, Calif., USA. loic.boussel@gmail.com
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Multicenter Study,
Research Support, N.I.H., Extramural
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