rdf:type |
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lifeskim:mentions |
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pubmed:issue |
9
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pubmed:dateCreated |
2009-8-26
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pubmed:abstractText |
The glucagon-like peptide-1 (GLP-1) receptor agonist, exendin-4, has previously been shown to delay the onset of diabetes when administered to Goto-Kakizaki (GK) rats in the prediabetic period. The present study aimed to evaluate whether long-term administration of exendin-4 to GK rats in the diabetic period would improve their diabetes and how glycaemic control was affected following drug wash-out.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Blood Glucose,
http://linkedlifedata.com/resource/pubmed/chemical/Hemoglobin A, Glycosylated,
http://linkedlifedata.com/resource/pubmed/chemical/Hypoglycemic Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Insulin,
http://linkedlifedata.com/resource/pubmed/chemical/Peptides,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Glucagon,
http://linkedlifedata.com/resource/pubmed/chemical/Venoms,
http://linkedlifedata.com/resource/pubmed/chemical/exenatide,
http://linkedlifedata.com/resource/pubmed/chemical/glucagon-like peptide receptor
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1463-1326
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
11
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
884-90
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:19508463-Animals,
pubmed-meshheading:19508463-Area Under Curve,
pubmed-meshheading:19508463-Blood Glucose,
pubmed-meshheading:19508463-Diabetes Mellitus, Type 2,
pubmed-meshheading:19508463-Disease Models, Animal,
pubmed-meshheading:19508463-Hemoglobin A, Glycosylated,
pubmed-meshheading:19508463-Hypoglycemic Agents,
pubmed-meshheading:19508463-Insulin,
pubmed-meshheading:19508463-Pancreas,
pubmed-meshheading:19508463-Peptides,
pubmed-meshheading:19508463-Rats,
pubmed-meshheading:19508463-Rats, Mutant Strains,
pubmed-meshheading:19508463-Rats, Wistar,
pubmed-meshheading:19508463-Receptors, Glucagon,
pubmed-meshheading:19508463-Venoms
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pubmed:year |
2009
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pubmed:articleTitle |
Long-term exendin-4 treatment delays natural deterioration of glycaemic control in diabetic Goto-Kakizaki rats.
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pubmed:affiliation |
Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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