|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
3
|
|
pubmed:dateCreated |
2010-2-8
|
|
pubmed:abstractText |
A cohort of postmenopausal osteoporotic females and controls with normal bone mineral density, the interleukin 6 (IL6) -634G > C (rs1800796) C allele of the promoter region showed association with osteoporosis. The lipoprotein receptor-related protein 5 (LRP5) gene showed association between C135242T C/T alleles and osteoporosis only in smokers, suggesting a role for environmental interaction.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Mar
|
|
pubmed:issn |
1433-2965
|
|
pubmed:author |
pubmed-author:GhebraniousNN,
pubmed-author:GiampietroP FPF,
pubmed-author:IvacicLL,
pubmed-author:KitchnerTT,
pubmed-author:LeVasseurJJ,
pubmed-author:LiuJJ,
pubmed-author:McCartyCC,
pubmed-author:McKiernanFF,
pubmed-author:MukeshBB,
pubmed-author:ShuldinerAA,
pubmed-author:WilsonDD
|
|
pubmed:issnType |
Electronic
|
|
pubmed:volume |
21
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
467-77
|
|
pubmed:dateRevised |
2011-11-17
|
|
pubmed:meshHeading |
pubmed-meshheading:19506792-Aged,
pubmed-meshheading:19506792-Body Mass Index,
pubmed-meshheading:19506792-Bone Density,
pubmed-meshheading:19506792-Epidemiologic Methods,
pubmed-meshheading:19506792-Female,
pubmed-meshheading:19506792-Gene Frequency,
pubmed-meshheading:19506792-Genetic Predisposition to Disease,
pubmed-meshheading:19506792-Genotype,
pubmed-meshheading:19506792-Humans,
pubmed-meshheading:19506792-Hydroxymethylglutaryl-CoA Reductase Inhibitors,
pubmed-meshheading:19506792-Interleukin-6,
pubmed-meshheading:19506792-LDL-Receptor Related Proteins,
pubmed-meshheading:19506792-Low Density Lipoprotein Receptor-Related Protein-5,
pubmed-meshheading:19506792-Middle Aged,
pubmed-meshheading:19506792-Osteoporosis, Postmenopausal,
pubmed-meshheading:19506792-Polymorphism, Single Nucleotide,
pubmed-meshheading:19506792-Postmenopause,
pubmed-meshheading:19506792-Smoking,
pubmed-meshheading:19506792-Wisconsin
|
|
pubmed:year |
2010
|
|
pubmed:articleTitle |
The role of cigarette smoking and statins in the development of postmenopausal osteoporosis: a pilot study utilizing the Marshfield Clinic Personalized Medicine Cohort.
|
|
pubmed:affiliation |
Marshfield Clinic, Department of Medical Genetic Services, 1000 North Oak Avenue, Marshfield, WI 54449, USA. pfgiampietro@pediatrics.wisc.edu
|
|
pubmed:publicationType |
Journal Article,
Review,
Research Support, Non-U.S. Gov't
|
