Source:http://linkedlifedata.com/resource/pubmed/id/19506096
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
2009-7-23
|
| pubmed:abstractText |
Carotid-femoral pulse wave velocity (PWV) is considered the gold-standard measurement of arterial stiffness. Obesity, however, can render inaccurate the measurement of PWV by external noninvasive devices. Phase-contrast MRI allows the determination of aortic PWV in multiple aortic locations with intra-arterial distance measurements, as well as the assessment of aortic mechanical properties. The purpose of this study was to assess the reliability of external carotid-femoral PWV values measured by well-validated external devices in comparison with MRI acquisitions of PWV and aortic mechanical properties in a population of obese subjects. PWV was measured with PulsePen and Complior II devices in 32 volunteers (18 men and 14 women), aged 46 to 65 years (mean: 55.7+/-5.1 years), presenting with isolated abdominal obesity, with a waist circumference >102 cm for men and >88 cm for women, and a body mass index between 27 and 35. These results were then compared with MRI PWV values and cross-sectional MRI thoracic aorta distensibility values. MRI PWV values were positively correlated with PWV measured by both PulsePen (r=0.47; P=0.005) and Complior (r=0.43; P=0.01). Aortic cross-sectional stiffness was positively correlated with PulsePen PWV (r=0.42; P=0.02). The same trend was also observed with Complior PWV (r=0.33; P=0.06). This is the first study comparing transcutaneous PWV measurements with MRI aortic elastic properties in obese subjects. Our results indicate that, for body mass index values < or =35 kg m(-2), PWV measured externally with Complior or PulsePen validly reflect values obtained directly in the thoracic aorta through MRI.
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| pubmed:commentsCorrections | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Aug
|
| pubmed:issn |
1524-4563
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| pubmed:author |
pubmed-author:BenetosAthanaseA,
pubmed-author:JolyLaureL,
pubmed-author:KarcherGillesG,
pubmed-author:Kearney-SchwartzAnnaA,
pubmed-author:MandryDamienD,
pubmed-author:MariePierre-YvesPY,
pubmed-author:Perret-GuillaumeChristineC,
pubmed-author:RossignolPatrickP,
pubmed-author:SalviPaoloP,
pubmed-author:ZannadFaiezF
|
| pubmed:issnType |
Electronic
|
| pubmed:volume |
54
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
421-6
|
| pubmed:dateRevised |
2009-10-26
|
| pubmed:meshHeading |
pubmed-meshheading:19506096-Abdominal Wall,
pubmed-meshheading:19506096-Analysis of Variance,
pubmed-meshheading:19506096-Aorta, Abdominal,
pubmed-meshheading:19506096-Blood Flow Velocity,
pubmed-meshheading:19506096-Body Mass Index,
pubmed-meshheading:19506096-Contrast Media,
pubmed-meshheading:19506096-Elasticity,
pubmed-meshheading:19506096-Female,
pubmed-meshheading:19506096-Hemodynamics,
pubmed-meshheading:19506096-Humans,
pubmed-meshheading:19506096-Magnetic Resonance Imaging,
pubmed-meshheading:19506096-Male,
pubmed-meshheading:19506096-Middle Aged,
pubmed-meshheading:19506096-Obesity,
pubmed-meshheading:19506096-Probability,
pubmed-meshheading:19506096-Prospective Studies,
pubmed-meshheading:19506096-Pulsatile Flow,
pubmed-meshheading:19506096-Statistics, Nonparametric,
pubmed-meshheading:19506096-Vascular Resistance,
pubmed-meshheading:19506096-Waist Circumference
|
| pubmed:year |
2009
|
| pubmed:articleTitle |
Pulse wave velocity assessment by external noninvasive devices and phase-contrast magnetic resonance imaging in the obese.
|
| pubmed:affiliation |
Centre de Gériatrie et Médecine Interne, CHU de Nancy, Rue du Morvan, 54511 Vandoeuvre les Nancy, France.
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| pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|