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rdf:type |
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lifeskim:mentions |
umls-concept:C0017262,
umls-concept:C0185117,
umls-concept:C0242184,
umls-concept:C0853879,
umls-concept:C0871261,
umls-concept:C1412812,
umls-concept:C1704632,
umls-concept:C1706817,
umls-concept:C1707520,
umls-concept:C2348519,
umls-concept:C2911684,
umls-concept:C2911692
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pubmed:dateCreated |
2009-7-13
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pubmed:abstractText |
Bcl-2/adenovirus E1B 19 kDa-interacting protein 3 (BNIP3) is a pro-apoptotic member of the Bcl-2 family induced under hypoxia. Low or absent expression has recently been described in human tumors, including gastrointestinal tumors, resulting in poor prognosis. Little is known about BNIP3 expression in invasive breast cancer. The aim of the present study was to investigate the expression of BNIP3 in invasive breast cancer at the mRNA and protein level in correlation with the hypoxic response and clinicopathological features.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/19505343-10467396,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19505343-10891486,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19505343-10922063,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19505343-11120745,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19505343-11156414,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19505343-11550088,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19505343-11559532,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19505343-11832486,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19505343-12242180,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19505343-12405945,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19505343-12627523,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19505343-14648660,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19505343-15289340,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19505343-15328198,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19505343-15677538,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19505343-15709167,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19505343-15756280,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19505343-15856026,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19505343-15906272,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19505343-1592381,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19505343-15942716,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19505343-16217754,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19505343-16357180,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19505343-16585181,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19505343-17255267,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19505343-1757079,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19505343-17805942,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19505343-18059169,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19505343-18163427,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19505343-19273585,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19505343-2050366,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19505343-9916985
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/BNIP3 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Carbonic Anhydrases,
http://linkedlifedata.com/resource/pubmed/chemical/Glucose Transporter Type 1,
http://linkedlifedata.com/resource/pubmed/chemical/HIF1A protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Hypoxia-Inducible Factor 1, alpha...,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Proto-Oncogene Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/SLC2A1 protein, human
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pubmed:status |
MEDLINE
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pubmed:issn |
1471-2407
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
9
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
175
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pubmed:dateRevised |
2010-9-27
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pubmed:meshHeading |
pubmed-meshheading:19505343-Anoxia,
pubmed-meshheading:19505343-Apoptosis,
pubmed-meshheading:19505343-Breast Neoplasms,
pubmed-meshheading:19505343-Carbonic Anhydrases,
pubmed-meshheading:19505343-Gene Expression Profiling,
pubmed-meshheading:19505343-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:19505343-Glucose Transporter Type 1,
pubmed-meshheading:19505343-Humans,
pubmed-meshheading:19505343-Hypoxia-Inducible Factor 1, alpha Subunit,
pubmed-meshheading:19505343-In Situ Hybridization,
pubmed-meshheading:19505343-Lymphatic Metastasis,
pubmed-meshheading:19505343-Membrane Proteins,
pubmed-meshheading:19505343-Neoplasm Invasiveness,
pubmed-meshheading:19505343-Prognosis,
pubmed-meshheading:19505343-Proto-Oncogene Proteins,
pubmed-meshheading:19505343-RNA, Messenger
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pubmed:year |
2009
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pubmed:articleTitle |
Expression of BNIP3 in invasive breast cancer: correlations with the hypoxic response and clinicopathological features.
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pubmed:affiliation |
Department of Pathology, University Medical Center, Utrecht, The Netherlands. e.koop@gelre.nl
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
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