| pubmed-article:19501931 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:19501931 | lifeskim:mentions | umls-concept:C0026809 | lld:lifeskim |
| pubmed-article:19501931 | lifeskim:mentions | umls-concept:C0383327 | lld:lifeskim |
| pubmed-article:19501931 | lifeskim:mentions | umls-concept:C0160390 | lld:lifeskim |
| pubmed-article:19501931 | lifeskim:mentions | umls-concept:C0030685 | lld:lifeskim |
| pubmed-article:19501931 | lifeskim:mentions | umls-concept:C0680255 | lld:lifeskim |
| pubmed-article:19501931 | lifeskim:mentions | umls-concept:C0205263 | lld:lifeskim |
| pubmed-article:19501931 | lifeskim:mentions | umls-concept:C0391871 | lld:lifeskim |
| pubmed-article:19501931 | lifeskim:mentions | umls-concept:C1283071 | lld:lifeskim |
| pubmed-article:19501931 | lifeskim:mentions | umls-concept:C1963578 | lld:lifeskim |
| pubmed-article:19501931 | lifeskim:mentions | umls-concept:C2346841 | lld:lifeskim |
| pubmed-article:19501931 | lifeskim:mentions | umls-concept:C1880177 | lld:lifeskim |
| pubmed-article:19501931 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:19501931 | pubmed:dateCreated | 2009-6-30 | lld:pubmed |
| pubmed-article:19501931 | pubmed:abstractText | After treatment with heat-killed Propionibacterium acnes mice show dense hepatic granuloma formation. Such mice develop liver injury in an interleukin (IL)-18-dependent manner after challenge with a sublethal dose LPS. As previously shown, LPS-stimulated Kupffer cells secrete IL-18 depending on caspase-1 and Toll-like receptor (TLR)-4 but independently of its signal adaptor myeloid differentiation factor 88 (MyD88), suggesting importance of another signal adaptor TIR domain-containing adapter inducing IFN-beta (TRIF). Nalp3 inflammasome reportedly controls caspase-1 activation. Here we investigated the roles of MyD88 and TRIF in P. acnes-induced hepatic granuloma formation and LPS-induced caspase-1 activation for IL-18 release. | lld:pubmed |
| pubmed-article:19501931 | pubmed:language | eng | lld:pubmed |
| pubmed-article:19501931 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19501931 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:19501931 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19501931 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19501931 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19501931 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19501931 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19501931 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19501931 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19501931 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19501931 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19501931 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19501931 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19501931 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19501931 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19501931 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:19501931 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:19501931 | pubmed:issn | 0168-8278 | lld:pubmed |
| pubmed-article:19501931 | pubmed:author | pubmed-author:AkiraShizuoS | lld:pubmed |
| pubmed-article:19501931 | pubmed:author | pubmed-author:TschoppJurgJ | lld:pubmed |
| pubmed-article:19501931 | pubmed:author | pubmed-author:YamamotoTetsu... | lld:pubmed |
| pubmed-article:19501931 | pubmed:author | pubmed-author:TsutsuiHiroko... | lld:pubmed |
| pubmed-article:19501931 | pubmed:author | pubmed-author:NakanishiKenj... | lld:pubmed |
| pubmed-article:19501931 | pubmed:author | pubmed-author:FujimotoJiroJ | lld:pubmed |
| pubmed-article:19501931 | pubmed:author | pubmed-author:Van... | lld:pubmed |
| pubmed-article:19501931 | pubmed:author | pubmed-author:MitaniKeikoK | lld:pubmed |
| pubmed-article:19501931 | pubmed:author | pubmed-author:Yumikura-Futa... | lld:pubmed |
| pubmed-article:19501931 | pubmed:author | pubmed-author:YasudaKoubunK | lld:pubmed |
| pubmed-article:19501931 | pubmed:author | pubmed-author:HayashiShuhei... | lld:pubmed |
| pubmed-article:19501931 | pubmed:author | pubmed-author:UchiyamaRyosu... | lld:pubmed |
| pubmed-article:19501931 | pubmed:author | pubmed-author:ImamuraMichik... | lld:pubmed |
| pubmed-article:19501931 | pubmed:author | pubmed-author:TaniguchiShun... | lld:pubmed |
| pubmed-article:19501931 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:19501931 | pubmed:volume | 51 | lld:pubmed |
| pubmed-article:19501931 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:19501931 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:19501931 | pubmed:pagination | 333-41 | lld:pubmed |
| pubmed-article:19501931 | pubmed:meshHeading | pubmed-meshheading:19501931... | lld:pubmed |
| pubmed-article:19501931 | pubmed:meshHeading | pubmed-meshheading:19501931... | lld:pubmed |
| pubmed-article:19501931 | pubmed:meshHeading | pubmed-meshheading:19501931... | lld:pubmed |
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| pubmed-article:19501931 | pubmed:meshHeading | pubmed-meshheading:19501931... | lld:pubmed |
| pubmed-article:19501931 | pubmed:meshHeading | pubmed-meshheading:19501931... | lld:pubmed |
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| pubmed-article:19501931 | pubmed:meshHeading | pubmed-meshheading:19501931... | lld:pubmed |
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| pubmed-article:19501931 | pubmed:meshHeading | pubmed-meshheading:19501931... | lld:pubmed |
| pubmed-article:19501931 | pubmed:meshHeading | pubmed-meshheading:19501931... | lld:pubmed |
| pubmed-article:19501931 | pubmed:meshHeading | pubmed-meshheading:19501931... | lld:pubmed |
| pubmed-article:19501931 | pubmed:meshHeading | pubmed-meshheading:19501931... | lld:pubmed |
| pubmed-article:19501931 | pubmed:meshHeading | pubmed-meshheading:19501931... | lld:pubmed |
| pubmed-article:19501931 | pubmed:meshHeading | pubmed-meshheading:19501931... | lld:pubmed |
| pubmed-article:19501931 | pubmed:meshHeading | pubmed-meshheading:19501931... | lld:pubmed |
| pubmed-article:19501931 | pubmed:meshHeading | pubmed-meshheading:19501931... | lld:pubmed |
| pubmed-article:19501931 | pubmed:meshHeading | pubmed-meshheading:19501931... | lld:pubmed |
| pubmed-article:19501931 | pubmed:year | 2009 | lld:pubmed |
| pubmed-article:19501931 | pubmed:articleTitle | Contribution of TIR domain-containing adapter inducing IFN-beta-mediated IL-18 release to LPS-induced liver injury in mice. | lld:pubmed |
| pubmed-article:19501931 | pubmed:affiliation | Department of Surgery, Hyogo College of Medicine, Nishinomiya, Japan. | lld:pubmed |
| pubmed-article:19501931 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:19501931 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:19501931 | lld:pubmed |
