|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
3
|
|
pubmed:dateCreated |
2009-6-5
|
|
pubmed:abstractText |
Caffeine can safely enhance the cytocidal effects of anticancer drugs through its DNA repair-inhibiting effect. We have demonstrated in several studies that caffeine-potentiated chemotherapy induces a high complete response rate in patients with osteosarcoma. The present study focused on monitoring and adjusting serum caffeine levels during caffeine-potentiated chemotherapy to reduce adverse effects.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
May
|
|
pubmed:issn |
1436-2023
|
|
pubmed:author |
|
|
pubmed:issnType |
Electronic
|
|
pubmed:volume |
14
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
253-8
|
|
pubmed:meshHeading |
pubmed-meshheading:19499290-Adolescent,
pubmed-meshheading:19499290-Adult,
pubmed-meshheading:19499290-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:19499290-Biological Markers,
pubmed-meshheading:19499290-Caffeine,
pubmed-meshheading:19499290-Child,
pubmed-meshheading:19499290-Child, Preschool,
pubmed-meshheading:19499290-Cisplatin,
pubmed-meshheading:19499290-Disease-Free Survival,
pubmed-meshheading:19499290-Dose-Response Relationship, Drug,
pubmed-meshheading:19499290-Doxorubicin,
pubmed-meshheading:19499290-Drug Synergism,
pubmed-meshheading:19499290-Female,
pubmed-meshheading:19499290-Humans,
pubmed-meshheading:19499290-Infusions, Intra-Arterial,
pubmed-meshheading:19499290-Male,
pubmed-meshheading:19499290-Middle Aged,
pubmed-meshheading:19499290-Osteosarcoma,
pubmed-meshheading:19499290-Young Adult
|
|
pubmed:year |
2009
|
|
pubmed:articleTitle |
Impact of serum caffeine monitoring on adverse effects and chemotherapeutic responses to caffeine-potentiated chemotherapy for osteosarcoma.
|
|
pubmed:affiliation |
Department of Orthopaedic Surgery, Graduate School of Medical Science, Kanazawa University, 13-1 Takaramachi, Kanazawa 920-8641, Japan.
|
|
pubmed:publicationType |
Journal Article
|
