| pubmed-article:19497068 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:19497068 | lifeskim:mentions | umls-concept:C0022671 | lld:lifeskim |
| pubmed-article:19497068 | lifeskim:mentions | umls-concept:C0017668 | lld:lifeskim |
| pubmed-article:19497068 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:19497068 | lifeskim:mentions | umls-concept:C0034897 | lld:lifeskim |
| pubmed-article:19497068 | lifeskim:mentions | umls-concept:C0205174 | lld:lifeskim |
| pubmed-article:19497068 | lifeskim:mentions | umls-concept:C0332206 | lld:lifeskim |
| pubmed-article:19497068 | pubmed:issue | 11 | lld:pubmed |
| pubmed-article:19497068 | pubmed:dateCreated | 2009-10-5 | lld:pubmed |
| pubmed-article:19497068 | pubmed:abstractText | Recurrent focal segmental glomerulosclerosis (FSGS) after renal transplantation with nephrotic syndrome is a serious problem with a high risk of graft loss. The therapeutic role of renin-angiotensin-system (RAS) blockers in recurrent FSGS is not clear. We present the safety and efficacy of an intensified triple RAS blockade with an ACE-inhibitor, an AT 1 receptor blocker and the direct renin inhibitor aliskiren in a 29-year-old renal transplant recipient with biopsy proven recurrence of FSGS and relapsing severe nephrotic syndrome. We subsequently used full dose ramipril, candesartan and aliskiren under a close monitoring of kidney function and electrolytes and examined the effect on proteinuria, clinical course and tolerability over 12 months. We found a significant and sustained antiproteinuric effect under triple RAS blockade. RAS blockade was generally well tolerated. This can offer a new therapeutic approach in selected hypertensive patients with recurrent FSGS. | lld:pubmed |
| pubmed-article:19497068 | pubmed:language | eng | lld:pubmed |
| pubmed-article:19497068 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19497068 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:19497068 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19497068 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19497068 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19497068 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19497068 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19497068 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19497068 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19497068 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19497068 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19497068 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19497068 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19497068 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19497068 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19497068 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:19497068 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:19497068 | pubmed:issn | 1432-2277 | lld:pubmed |
| pubmed-article:19497068 | pubmed:author | pubmed-author:FrankHelgaH | lld:pubmed |
| pubmed-article:19497068 | pubmed:author | pubmed-author:AmannKerstinK | lld:pubmed |
| pubmed-article:19497068 | pubmed:author | pubmed-author:HeemannUweU | lld:pubmed |
| pubmed-article:19497068 | pubmed:author | pubmed-author:FreibergerVer... | lld:pubmed |
| pubmed-article:19497068 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:19497068 | pubmed:volume | 22 | lld:pubmed |
| pubmed-article:19497068 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:19497068 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:19497068 | pubmed:pagination | 1110-3 | lld:pubmed |
| pubmed-article:19497068 | pubmed:dateRevised | 2010-11-18 | lld:pubmed |
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| pubmed-article:19497068 | pubmed:meshHeading | pubmed-meshheading:19497068... | lld:pubmed |
| pubmed-article:19497068 | pubmed:year | 2009 | lld:pubmed |
| pubmed-article:19497068 | pubmed:articleTitle | Effect of a triple blockade of the renin-angiotensin-system in recurrent focal segmental glomerulosclerosis after kidney transplantation. | lld:pubmed |
| pubmed-article:19497068 | pubmed:affiliation | Department of Nephrology, Klinikum rechts der Isar, Technische Universitaet Muenchen, Munich, Germany. | lld:pubmed |
| pubmed-article:19497068 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:19497068 | pubmed:publicationType | Case Reports | lld:pubmed |
