rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
8
|
pubmed:dateCreated |
2009-8-21
|
pubmed:abstractText |
Immediate allergic hypersensitivity reactions with fentanyl are rarely reported. We diagnosed a presumably IgE-mediated allergic hypersensitivity reaction comprising generalized erythema and bronchospasm 4 h after the first-time application of transdermal fentanyl. Prick test remained negative with fentanyl whereas an intradermal test (IDT) with fentanyl was positive (dilution 10(-2)). Cross-reactivity was found with sufentanil but not with remifentanil. The diagnosis was supported by the clinical history and a positive IDT with fentanyl. This case report confirms the need for a systematic allergological investigation in case of immediate hypersensitivity reactions for all drugs and all modes of administration.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Sep
|
pubmed:issn |
1399-6576
|
pubmed:author |
|
pubmed:issnType |
Electronic
|
pubmed:volume |
53
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1092-3
|
pubmed:meshHeading |
pubmed-meshheading:19496758-Administration, Cutaneous,
pubmed-meshheading:19496758-Albuterol,
pubmed-meshheading:19496758-Analgesics, Opioid,
pubmed-meshheading:19496758-Anaphylaxis,
pubmed-meshheading:19496758-Bariatric Surgery,
pubmed-meshheading:19496758-Bronchial Spasm,
pubmed-meshheading:19496758-Bronchodilator Agents,
pubmed-meshheading:19496758-Cross Reactions,
pubmed-meshheading:19496758-Drug Hypersensitivity,
pubmed-meshheading:19496758-Erythema,
pubmed-meshheading:19496758-Female,
pubmed-meshheading:19496758-Fentanyl,
pubmed-meshheading:19496758-Humans,
pubmed-meshheading:19496758-Immunoglobulin E,
pubmed-meshheading:19496758-Middle Aged,
pubmed-meshheading:19496758-Skin Tests
|
pubmed:year |
2009
|
pubmed:articleTitle |
An anaphylactic reaction to transdermal delivered fentanyl.
|
pubmed:affiliation |
Service d'Anesthésie-Réanimation Chirurgicale & SAMU de Paris, Hôpital Necker-Enfants Malades, AP-HP, Université Paris Descartes, Paris, France. pascale.dewachter@yahoo.fr
|
pubmed:publicationType |
Journal Article,
Case Reports
|