Source:http://linkedlifedata.com/resource/pubmed/id/19496734
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7
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pubmed:dateCreated |
2009-7-6
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pubmed:abstractText |
There is accumulating evidence from the epidemiological field of telomere biology that telomere length plays an important role in the pathophysiology of cardiovascular disease. The RNA-dependent DNA polymerase, telomerase, is essential in regulating telomere length by acting as a reverse transcriptase. However, the relationship between telomerase activity and telomere length in cardiovascular disease is unclear. This is due, in part, to the paucity of information on the utility of a quantitative and routine assay for the determination of telomerase activity in circulating blood leukocytes.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
1434-6621
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
47
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
870-3
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pubmed:meshHeading |
pubmed-meshheading:19496734-Adult,
pubmed-meshheading:19496734-Cardiovascular Diseases,
pubmed-meshheading:19496734-Cell Count,
pubmed-meshheading:19496734-Epidemiologic Studies,
pubmed-meshheading:19496734-Humans,
pubmed-meshheading:19496734-Leukocytes,
pubmed-meshheading:19496734-Male,
pubmed-meshheading:19496734-Nucleic Acid Amplification Techniques,
pubmed-meshheading:19496734-Reagent Kits, Diagnostic,
pubmed-meshheading:19496734-Repetitive Sequences, Nucleic Acid,
pubmed-meshheading:19496734-Telomerase,
pubmed-meshheading:19496734-Telomere
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pubmed:year |
2009
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pubmed:articleTitle |
Quantitative telomerase activity in circulating human leukocytes: utility of real-time telomeric repeats amplification protocol (RQ-TRAP) in a clinical/epidemiological setting.
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pubmed:affiliation |
Division of Endocrinology, Diabetes and Hypertension, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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