Linked Life Data

19496686

Source:http://linkedlifedata.com/resource/pubmed/id/19496686

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2009-6-5
pubmed:abstractText
The combination of aphasia and epileptic seizures is characteristic for Landau-Kleffner syndrome and childhood disintegrative disorder. These disorders affect young children with previously normal psychomotor development, causing profound regression with loss of receptive and expressive language capabilities. The etiologies of these childhood epilepsy-aphasia syndromes are largely unknown, and the long-term prognosis is poor. The seizures usually remit in adolescence, however most patients show persistent language dysfunction. In autosomal dominant lateral temporal lobe epilepsy, the aphasic symptoms are transitory and mostly restricted to the ictal phase. The monogenic etiology of this rare seizure disorder offers the possibility to study the molecular basis of epilepsy-aphasia syndromes.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
1744-8360
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
9
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
825-33
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Epilepsy-aphasia syndromes.
pubmed:affiliation
Ludwig-Maximilians-University of Münich, School of Medicine, Institute of Human Genetics, Goethestrasse 29, 80336 Münich, Germany. ortrud.steinlein@med.uni-muenchen.de
pubmed:publicationType
Journal Article, Review