19495943

Source:http://linkedlifedata.com/resource/pubmed/id/19495943

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0005528, umls-concept:C0182400, umls-concept:C0201734, umls-concept:C0220825, umls-concept:C0296800, umls-concept:C0542341, umls-concept:C0679083, umls-concept:C0870071, umls-concept:C1158478, umls-concept:C1516606, umls-concept:C1705422, umls-concept:C1709630
pubmed:issue	8
pubmed:dateCreated	2009-7-6
pubmed:abstractText	The suitability of fexofenadine as a probe substrate to assess hepatobiliary transport function in humans was evaluated by pharmacokinetic modeling/simulation and in vitro/in situ studies using chemical modulators.
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/R01 GM041935-17, http://linkedlifedata.com/resource/pubmed/grant/R01 GM41935
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pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/8406521
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Histamine H1 Antagonists..., http://linkedlifedata.com/resource/pubmed/chemical/Molecular Probes, http://linkedlifedata.com/resource/pubmed/chemical/Terfenadine, http://linkedlifedata.com/resource/pubmed/chemical/fexofenadine
pubmed:status	MEDLINE
pubmed:month	Aug
pubmed:issn	1573-904X
pubmed:author	pubmed-author:BrouwerKim L RKL, pubmed-author:SwiftBrandonB, pubmed-author:TianXianbinX
pubmed:issnType	Electronic
pubmed:volume	26
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	1942-51
pubmed:dateRevised	2011-7-28
pubmed:meshHeading	pubmed-meshheading:19495943-Animals, pubmed-meshheading:19495943-Biliary Tract, pubmed-meshheading:19495943-Cells, Cultured, pubmed-meshheading:19495943-Histamine H1 Antagonists, Non-Sedating, pubmed-meshheading:19495943-Humans, pubmed-meshheading:19495943-Liver, pubmed-meshheading:19495943-Models, Biological, pubmed-meshheading:19495943-Molecular Probes, pubmed-meshheading:19495943-Rats, pubmed-meshheading:19495943-Rats, Wistar, pubmed-meshheading:19495943-Terfenadine
pubmed:year	2009
pubmed:articleTitle	Integration of preclinical and clinical data with pharmacokinetic modeling and simulation to evaluate fexofenadine as a probe for hepatobiliary transport function.
pubmed:affiliation	Division of Pharmacotherapy and Experimental Therapeutics, Eshelman School of Pharmacy, The University of North Carolina at Chapel Hill, 311 Pharmacy Lane, C.B. #7360 Kerr Hall, Chapel Hill, North Carolina 27599-7360, USA.
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural