19495753

Source:http://linkedlifedata.com/resource/pubmed/id/19495753

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0006142, umls-concept:C0027651, umls-concept:C0033262, umls-concept:C0043047, umls-concept:C0205314, umls-concept:C0520484, umls-concept:C0679622, umls-concept:C0683598, umls-concept:C1516155, umls-concept:C1749467
pubmed:issue	2
pubmed:dateCreated	2011-4-6
pubmed:abstractText	Identification of a novel topoisomerase I inhibitor which shows superior efficacy and less individual variation than irinotecan hydrochloride (CPT-11).
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/7806519
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/ABCG2 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/ATP-Binding Cassette Transporters, http://linkedlifedata.com/resource/pubmed/chemical/Acetylcholinesterase, http://linkedlifedata.com/resource/pubmed/chemical/Antineoplastic Agents, http://linkedlifedata.com/resource/pubmed/chemical/CH 0793076, http://linkedlifedata.com/resource/pubmed/chemical/Camptothecin, http://linkedlifedata.com/resource/pubmed/chemical/Dipeptides, http://linkedlifedata.com/resource/pubmed/chemical/Heterocyclic Compounds with 4 or..., http://linkedlifedata.com/resource/pubmed/chemical/Neoplasm Proteins, http://linkedlifedata.com/resource/pubmed/chemical/Prodrugs, http://linkedlifedata.com/resource/pubmed/chemical/Water, http://linkedlifedata.com/resource/pubmed/chemical/irinotecan
pubmed:status	MEDLINE
pubmed:month	Jan
pubmed:issn	1432-0843
pubmed:author	pubmed-author:EndoMikaM, pubmed-author:MiwaMasanoriM, pubmed-author:MiyazakiYokoY, pubmed-author:MurataTakeshiT, pubmed-author:NagaoShunsukeS, pubmed-author:NanbaEitaroE, pubmed-author:NiizumaSatoshiS, pubmed-author:OgawaKotaroK, pubmed-author:OhwadaJunJ, pubmed-author:OzawaSawakoS, pubmed-author:ShimmaNobuoN, pubmed-author:SudaHitomiH, pubmed-author:TaniguchiKenjiK, pubmed-author:TanimuraHiromiH, pubmed-author:TsukazakiMasaoM, pubmed-author:UraMasakoM, pubmed-author:Yamada-OkabeHisafumiH
pubmed:issnType	Electronic
pubmed:volume	65
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	363-71
pubmed:meshHeading	pubmed-meshheading:19495753-ATP-Binding Cassette Transporters, pubmed-meshheading:19495753-Acetylcholinesterase, pubmed-meshheading:19495753-Animals, pubmed-meshheading:19495753-Antineoplastic Agents, pubmed-meshheading:19495753-Camptothecin, pubmed-meshheading:19495753-Cell Line, Tumor, pubmed-meshheading:19495753-Dipeptides, pubmed-meshheading:19495753-Drug Resistance, Neoplasm, pubmed-meshheading:19495753-Drug Synergism, pubmed-meshheading:19495753-Heterocyclic Compounds with 4 or More Rings, pubmed-meshheading:19495753-Humans, pubmed-meshheading:19495753-Male, pubmed-meshheading:19495753-Mice, pubmed-meshheading:19495753-Mice, Nude, pubmed-meshheading:19495753-Neoplasm Proteins, pubmed-meshheading:19495753-Prodrugs, pubmed-meshheading:19495753-Solubility, pubmed-meshheading:19495753-Water, pubmed-meshheading:19495753-Xenograft Model Antitumor Assays
pubmed:year	2010
pubmed:articleTitle	A water soluble prodrug of a novel camptothecin analog is efficacious against breast cancer resistance protein-expressing tumor xenografts.
pubmed:affiliation	Kamakura Research Laboratories, Pharmaceutical Research Department, Chugai Pharmaceutical Co. Ltd., Kajiwara, Kanagawa, Japan.
pubmed:publicationType	Journal Article