| pubmed-article:19490972 | rdf:type | pubmed:Citation | lld:pubmed |
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| pubmed-article:19490972 | lifeskim:mentions | umls-concept:C0031809 | lld:lifeskim |
| pubmed-article:19490972 | lifeskim:mentions | umls-concept:C0017431 | lld:lifeskim |
| pubmed-article:19490972 | lifeskim:mentions | umls-concept:C0039593 | lld:lifeskim |
| pubmed-article:19490972 | lifeskim:mentions | umls-concept:C1274040 | lld:lifeskim |
| pubmed-article:19490972 | lifeskim:mentions | umls-concept:C0022877 | lld:lifeskim |
| pubmed-article:19490972 | lifeskim:mentions | umls-concept:C0683598 | lld:lifeskim |
| pubmed-article:19490972 | lifeskim:mentions | umls-concept:C1522326 | lld:lifeskim |
| pubmed-article:19490972 | lifeskim:mentions | umls-concept:C1292734 | lld:lifeskim |
| pubmed-article:19490972 | lifeskim:mentions | umls-concept:C0003980 | lld:lifeskim |
| pubmed-article:19490972 | lifeskim:mentions | umls-concept:C0332306 | lld:lifeskim |
| pubmed-article:19490972 | lifeskim:mentions | umls-concept:C1519193 | lld:lifeskim |
| pubmed-article:19490972 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:19490972 | pubmed:dateCreated | 2009-6-3 | lld:pubmed |
| pubmed-article:19490972 | pubmed:abstractText | The TREAT Asia (Therapeutics, Research, Education, and AIDS Training in Asia) Network is building capacity for Human Immunodeficiency Virus Type-1 (HIV-1) drug resistance testing in the region. The objective of the TREAT Asia Quality Assessment Scheme - designated TAQAS - is to standardize HIV-1 genotypic resistance testing (HIV genotyping) among laboratories to permit rigorous comparison of results from different clinics and testing centres. TAQAS has evaluated three panels of HIV-1-positive plasma from clinical material or low-passage, culture supernatant for up to 10 Asian laboratories. Laboratory participants used their standard protocols to perform HIV genotyping. Assessment was in comparison to a target genotype derived from all participants and the reference laboratory's result. Agreement between most participants at the edited nucleotide sequence level was high (>98%). Most participants performed to the reference laboratory standard in detection of drug resistance mutations (DRMs). However, there was variation in the detection of nucleotide mixtures (0-83%) and a significant correlation with the detection of DRMs (p<0.01). Interpretation of antiretroviral resistance showed approximately 70% agreement among participants when different interpretation systems were used but >90% agreement with a common interpretation system, within the Stanford University Drug Resistance Database. Using the principles of external quality assessment and a reference laboratory, TAQAS has demonstrated high quality HIV genotyping results from Asian laboratories. | lld:pubmed |
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| pubmed-article:19490972 | pubmed:language | eng | lld:pubmed |
| pubmed-article:19490972 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19490972 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:19490972 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:19490972 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:19490972 | pubmed:issn | 1879-0984 | lld:pubmed |
| pubmed-article:19490972 | pubmed:author | pubmed-author:OkaShinichiS | lld:pubmed |
| pubmed-article:19490972 | pubmed:author | pubmed-author:LawMatthewM | lld:pubmed |
| pubmed-article:19490972 | pubmed:author | pubmed-author:LandSallyS | lld:pubmed |
| pubmed-article:19490972 | pubmed:author | pubmed-author:KantorRamiR | lld:pubmed |
| pubmed-article:19490972 | pubmed:author | pubmed-author:KatzensteinDa... | lld:pubmed |
| pubmed-article:19490972 | pubmed:author | pubmed-author:DaxElizabeth... | lld:pubmed |
| pubmed-article:19490972 | pubmed:author | pubmed-author:CunninghamPhi... | lld:pubmed |
| pubmed-article:19490972 | pubmed:author | pubmed-author:SmithJefferyJ | lld:pubmed |
| pubmed-article:19490972 | pubmed:author | pubmed-author:SayerDavidD | lld:pubmed |
| pubmed-article:19490972 | pubmed:author | pubmed-author:ChenYi-Ming... | lld:pubmed |
| pubmed-article:19490972 | pubmed:author | pubmed-author:ZhouJialunJ | lld:pubmed |
| pubmed-article:19490972 | pubmed:author | pubmed-author:DeLongAllison... | lld:pubmed |
| pubmed-article:19490972 | pubmed:author | pubmed-author:FrostKevinK | lld:pubmed |
| pubmed-article:19490972 | pubmed:author | pubmed-author:TAQAS... | lld:pubmed |
| pubmed-article:19490972 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:19490972 | pubmed:volume | 159 | lld:pubmed |
| pubmed-article:19490972 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:19490972 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:19490972 | pubmed:pagination | 185-93 | lld:pubmed |
| pubmed-article:19490972 | pubmed:dateRevised | 2010-9-27 | lld:pubmed |
| pubmed-article:19490972 | pubmed:meshHeading | pubmed-meshheading:19490972... | lld:pubmed |
| pubmed-article:19490972 | pubmed:meshHeading | pubmed-meshheading:19490972... | lld:pubmed |
| pubmed-article:19490972 | pubmed:meshHeading | pubmed-meshheading:19490972... | lld:pubmed |
| pubmed-article:19490972 | pubmed:meshHeading | pubmed-meshheading:19490972... | lld:pubmed |
| pubmed-article:19490972 | pubmed:meshHeading | pubmed-meshheading:19490972... | lld:pubmed |
| pubmed-article:19490972 | pubmed:meshHeading | pubmed-meshheading:19490972... | lld:pubmed |
| pubmed-article:19490972 | pubmed:meshHeading | pubmed-meshheading:19490972... | lld:pubmed |
| pubmed-article:19490972 | pubmed:year | 2009 | lld:pubmed |
| pubmed-article:19490972 | pubmed:articleTitle | TREAT Asia Quality Assessment Scheme (TAQAS) to standardize the outcome of HIV genotypic resistance testing in a group of Asian laboratories. | lld:pubmed |
| pubmed-article:19490972 | pubmed:affiliation | National Serology Reference Laboratory, Australia. sally@nrl.gov.au | lld:pubmed |
| pubmed-article:19490972 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:19490972 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
