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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
8
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pubmed:dateCreated |
2009-7-15
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pubmed:abstractText |
CD163 is a monocyte/macrophage specific receptor whose soluble form (sCD163) is elevated in inflammatory diseases. Obesity is associated with chronic inflammation and low adiponectin, an anti-inflammatory adipokine. Adiponectin, 5-aminoimidazole-4-carboxamide-1-4-ribofuranoside (AICAR) and metformin activate the AMP-kinase that exerts anti-inflammatory effects, and the influence of adiponectin and these drugs on monocytic CD163 was analysed, and cellular and sCD163 were determined in obesity and type 2 diabetes.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/AICA ribonucleotide,
http://linkedlifedata.com/resource/pubmed/chemical/Adiponectin,
http://linkedlifedata.com/resource/pubmed/chemical/Aminoimidazole Carboxamide,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, Differentiation...,
http://linkedlifedata.com/resource/pubmed/chemical/CD163 antigen,
http://linkedlifedata.com/resource/pubmed/chemical/Hypoglycemic Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Metformin,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Cell Surface,
http://linkedlifedata.com/resource/pubmed/chemical/Ribonucleotides
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
1365-2362
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pubmed:author |
pubmed-author:BallFF,
pubmed-author:BuechlerCC,
pubmed-author:KoppAA,
pubmed-author:LiebererEE,
pubmed-author:NeumeierMM,
pubmed-author:SchäfflerAA,
pubmed-author:SporrerDD,
pubmed-author:StögbauerFF,
pubmed-author:WanningerJJ,
pubmed-author:WeberMM,
pubmed-author:WeigertJJ
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pubmed:issnType |
Electronic
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pubmed:volume |
39
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
671-9
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pubmed:meshHeading |
pubmed-meshheading:19490068-Adiponectin,
pubmed-meshheading:19490068-Adult,
pubmed-meshheading:19490068-Aminoimidazole Carboxamide,
pubmed-meshheading:19490068-Antigens, CD,
pubmed-meshheading:19490068-Antigens, Differentiation, Myelomonocytic,
pubmed-meshheading:19490068-Diabetes Mellitus, Type 2,
pubmed-meshheading:19490068-Down-Regulation,
pubmed-meshheading:19490068-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:19490068-Female,
pubmed-meshheading:19490068-Humans,
pubmed-meshheading:19490068-Hypoglycemic Agents,
pubmed-meshheading:19490068-Male,
pubmed-meshheading:19490068-Metformin,
pubmed-meshheading:19490068-Middle Aged,
pubmed-meshheading:19490068-Obesity,
pubmed-meshheading:19490068-Receptors, Cell Surface,
pubmed-meshheading:19490068-Ribonucleotides
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pubmed:year |
2009
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pubmed:articleTitle |
Adiponectin downregulates CD163 whose cellular and soluble forms are elevated in obesity.
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pubmed:affiliation |
Department of Internal Medicine I, Regensburg University Hospital, Regensburg, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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