Linked Life Data

1949000

Source:http://linkedlifedata.com/resource/pubmed/id/1949000

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-2
pubmed:dateCreated
1991-12-13
pubmed:abstractText
The weight of the major internal organs in 188 autopsy cases of Duchenne muscular dystrophy were studied in relation to the clinical course of disease and age of the patients at death. The hearts were classified into three groups (atrophic, normal weight and hypertrophic), each constituting about one-third of the total cases. Cardiac atrophy was most frequent in the older cases of more than 20 years of age, whereas hypertrophy was more frequent in younger cases with the highest incidence in cases under 15 years. The liver showed marked atrophy in most cases (144 of 178 cases). The incidence of liver atrophy increased with the age of the patients and all 55 patients of over 20 years of age had an abnormally small liver. These marked atrophies of the heart and liver appeared to have occurred in parallel with loss of body weight due to skeletal muscle wasting. Myocardial dystrophy might be another causative factor for cardiac atrophy. The myocardial hypertrophy seemed to be caused by an intercurrent congestive failure. Renal atrophy was observed in only a few of the extremely emaciated patients. The brain weight was within the normal range in most cases.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0040-8875
pubmed:author
pubmed:issnType
Print
pubmed:volume
38
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
5-13
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
Autopsy study on the weight of the heart, liver, kidney and brain in Duchenne muscular dystrophy.
pubmed:affiliation
1st Department of Pathology, School of Medicine, University of Tokushima, Japan.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't