Linked Life Data

19488986

Source:http://linkedlifedata.com/resource/pubmed/id/19488986

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2009-9-2
pubmed:abstractText
Accurate measurement of peak velocity is critical to the assessment of patients with stenotic valvular disease. Conventional phase contrast (PC) methods for imaging high-velocity jets in aortic stenosis are susceptible to intravoxel dephasing signal loss, which can result in unreliable measurements. The most effective method for reducing intravoxel dephasing is to shorten the echo time (TE); however, the amount that TE can be shortened in conventional sequences is limited. A new sequence incorporating velocity-dependent slice excitation and ultrashort TE (UTE) centric radial readout trajectories is proposed that reduces TE from 2.85 to 0.65 ms. In a high-velocity stenotic jet phantom, a conventional sequence had >5% flow error at a flow rate of only 400 mL/s (velocity >358 cm/s), whereas the PC-UTE showed excellent agreement (<5% error) at much higher flow rates (1080 mL/s, 965 cm/s). In vivo feasibility studies demonstrated that by measuring velocity over a shorter time the PC-UTE approach is more robust to intravoxel dephasing signal loss. It also has less inherent higher-order motion encoding. This sequence therefore demonstrates potential as a more robust method for measuring peak velocity and flow in high-velocity turbulent stenotic jets.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
1522-2594
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
62
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
626-36
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Phase contrast ultrashort TE: A more reliable technique for measurement of high-velocity turbulent stenotic jets.
pubmed:affiliation
Bioengineering Institute, University of Auckland, Auckland, New Zealand. k.obrien@auckland.ac.nz
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't