Source:http://linkedlifedata.com/resource/pubmed/id/19488461
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
2009-8-4
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pubmed:abstractText |
The treatment of malignant melanoma or sarcomas on a limb using extremity perfusion with tumour necrosis factor (TNF-alpha) and melphalan can result in a high degree of systemic toxicity if there is any leakage from the isolated blood territory of the limb into the systemic vascular territory. Leakage is currently controlled by using radiotracers and heavy external probes in a procedure that requires continuous manual calculations. The aim of this work was to develop a light, easily transportable system to monitor limb perfusion leakage by controlling systemic blood pool radioactivity with a portable gamma camera adapted for intraoperative use as an external probe, and to initiate its application in the treatment of MM patients.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0029-5566
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
48
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
166-72
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pubmed:meshHeading |
pubmed-meshheading:19488461-Disease-Free Survival,
pubmed-meshheading:19488461-Equipment Design,
pubmed-meshheading:19488461-Extremities,
pubmed-meshheading:19488461-Gamma Cameras,
pubmed-meshheading:19488461-Humans,
pubmed-meshheading:19488461-Melanoma,
pubmed-meshheading:19488461-Melphalan,
pubmed-meshheading:19488461-Monitoring, Intraoperative,
pubmed-meshheading:19488461-Neoplasm Metastasis,
pubmed-meshheading:19488461-Reproducibility of Results,
pubmed-meshheading:19488461-Sarcoma,
pubmed-meshheading:19488461-Survival Analysis,
pubmed-meshheading:19488461-Technetium,
pubmed-meshheading:19488461-Tumor Necrosis Factor-alpha
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pubmed:year |
2009
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pubmed:articleTitle |
Monitoring system for isolated limb perfusion based on a portable gamma camera.
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pubmed:affiliation |
Servei de Medicina Nuclear, Hospital Clinic, Barcelona, Spain.
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pubmed:publicationType |
Journal Article
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