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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2010-5-11
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pubmed:abstractText |
Alcohol has been traditionally considered a possible migraine trigger factor. Alcohol-dehydrogenase (ADH) enzymes are thought to play important roles in the metabolism of ethanol. Relevant polymorphism has been found only for 2 of the ADH genes (mapped on chromosome ): ADH 1B, betapolypeptide (ADH2) and ADH3. The polymorphism rs1229984, located in the third exon of the human ADH2 gene, causes the amino acid substitution Arg48His. The aim of this study was to investigate the possible association between ADH2 polymorphism and the risk for migraine and for triggering migraine attacks.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1526-4610
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
50
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
85-91
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pubmed:meshHeading |
pubmed-meshheading:19486361-Adult,
pubmed-meshheading:19486361-Alcohol Dehydrogenase,
pubmed-meshheading:19486361-Alcohol-Induced Disorders, Nervous System,
pubmed-meshheading:19486361-Brain,
pubmed-meshheading:19486361-Central Nervous System Depressants,
pubmed-meshheading:19486361-DNA Mutational Analysis,
pubmed-meshheading:19486361-Ethanol,
pubmed-meshheading:19486361-Female,
pubmed-meshheading:19486361-Gene Expression Regulation, Enzymologic,
pubmed-meshheading:19486361-Gene Frequency,
pubmed-meshheading:19486361-Genetic Markers,
pubmed-meshheading:19486361-Genetic Predisposition to Disease,
pubmed-meshheading:19486361-Genetic Testing,
pubmed-meshheading:19486361-Genetic Variation,
pubmed-meshheading:19486361-Genotype,
pubmed-meshheading:19486361-Humans,
pubmed-meshheading:19486361-Male,
pubmed-meshheading:19486361-Middle Aged,
pubmed-meshheading:19486361-Migraine Disorders,
pubmed-meshheading:19486361-Polymorphism, Genetic,
pubmed-meshheading:19486361-Risk Factors
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pubmed:year |
2010
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pubmed:articleTitle |
Alcohol dehydrogenase 2 genotype and risk for migraine.
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pubmed:affiliation |
Department of Biochemistry and Molecular Biology, School of Biological Sciences, University of Extremadura.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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