Linked Life Data

19486276

Source:http://linkedlifedata.com/resource/pubmed/id/19486276

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
2009-7-6
pubmed:abstractText
We have recently reported a novel mutation in the beta3 subunit of the platelet fibrinogen receptor (alpha(IIb)beta3D723H) identified in a patient with dominantly inherited macrothrombocytopenia, and we have shown that this mutation promotes a new phenotype in Chinese hamster ovary (CHO) cells, characterized by fibrinogen-dependent, microtubule-driven proplatelet-like cell extensions.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
1538-7836
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
7
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1207-17
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Overexpression of the partially activated alpha(IIb)beta3D723H integrin salt bridge mutant downregulates RhoA activity and induces microtubule-dependent proplatelet-like extensions in Chinese hamster ovary cells.
pubmed:affiliation
Laboratoire de Biologie et Physiologie Intégrée (CNRS/GDRE-ITI), University of Luxembourg, Grand-Duchy of Luxembourg, Luxembourg. elisabeth.schaffner@uni.lu
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't