rdf:type |
|
lifeskim:mentions |
umls-concept:C0005682,
umls-concept:C0034693,
umls-concept:C0034721,
umls-concept:C0042036,
umls-concept:C0234421,
umls-concept:C0441655,
umls-concept:C0597357,
umls-concept:C0806140,
umls-concept:C1419063,
umls-concept:C1554184,
umls-concept:C1709059
|
pubmed:issue |
1
|
pubmed:dateCreated |
2009-9-1
|
pubmed:abstractText |
Cyclooxygenase inhibitors function to reduce levels of prostaglandin E(2) (PGE(2)) and are broadly efficacious in models of bladder overactivity. We therefore investigated a regulation of urinary bladder function in conscious rats by modulation of the EP(3) receptor for PGE(2).
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/GR 63799X,
http://linkedlifedata.com/resource/pubmed/chemical/PTGER3 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Prostaglandins E, Synthetic,
http://linkedlifedata.com/resource/pubmed/chemical/Ptger3 protein, rat,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Prostaglandin E,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Prostaglandin E, EP3...
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pubmed:status |
MEDLINE
|
pubmed:month |
Sep
|
pubmed:issn |
1476-5381
|
pubmed:author |
|
pubmed:issnType |
Electronic
|
pubmed:volume |
158
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
372-81
|
pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:19486006-Animals,
pubmed-meshheading:19486006-Cell Line,
pubmed-meshheading:19486006-Consciousness,
pubmed-meshheading:19486006-Female,
pubmed-meshheading:19486006-Humans,
pubmed-meshheading:19486006-Prostaglandins E, Synthetic,
pubmed-meshheading:19486006-Rats,
pubmed-meshheading:19486006-Rats, Inbred SHR,
pubmed-meshheading:19486006-Receptors, Prostaglandin E,
pubmed-meshheading:19486006-Receptors, Prostaglandin E, EP3 Subtype,
pubmed-meshheading:19486006-Urinary Bladder,
pubmed-meshheading:19486006-Urination
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pubmed:year |
2009
|
pubmed:articleTitle |
Dual modulation of urinary bladder activity and urine flow by prostanoid EP3 receptors in the conscious rat.
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pubmed:affiliation |
Urogenital Biology, Cardiovascular and Urogenital Center for Excellence in Drug Discovery, GlaxoSmithKline Pharmaceuticals, King of Prussia, PA 19406, USA.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|