Source:http://linkedlifedata.com/resource/pubmed/id/19483734
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
2009-6-1
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pubmed:abstractText |
A randomized phase III trial evaluated the effect of adding lapatinib to paclitaxel as first-line therapy for patients with metastatic breast cancer whose tumors were negative or untested for human epidermal growth factor receptor 2 (HER2) overexpression. Progression-free survival was prolonged significantly in patients with HER2-overexpressing tumors, which indicates that lapatinib exerts its main effects via the HER2 pathway.
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pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1759-4782
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
6
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
308-9
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:19483734-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:19483734-Breast Neoplasms,
pubmed-meshheading:19483734-Clinical Trials, Phase III as Topic,
pubmed-meshheading:19483734-Female,
pubmed-meshheading:19483734-Humans,
pubmed-meshheading:19483734-Paclitaxel,
pubmed-meshheading:19483734-Quinazolines,
pubmed-meshheading:19483734-Randomized Controlled Trials as Topic,
pubmed-meshheading:19483734-Receptor, erbB-2
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pubmed:year |
2009
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pubmed:articleTitle |
Targeted therapies: Combined lapatinib and paclitaxel in HER2-positive breast cancer.
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pubmed:affiliation |
Division of Medicine, Instituto Nacional de Enfermedades Neoplásicas, Av. Angamos Este 2520, Surquillo, Lima 34, Peru.
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pubmed:publicationType |
Journal Article,
Comment
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