19483665

Source:http://linkedlifedata.com/resource/pubmed/id/19483665

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0022646, umls-concept:C0025598, umls-concept:C0042333, umls-concept:C0221102, umls-concept:C1280500, umls-concept:C1420137, umls-concept:C1420140
pubmed:issue	7
pubmed:dateCreated	2009-6-18
pubmed:abstractText	The goal of this study was to determine the effect of a genetic variant in the organic cation transporter 2 (OCT2), OCT2-808G/T, which results in an amino acid change, A270S, on the pharmacokinetics of the antidiabetic drug, metformin.
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/GM61390, http://linkedlifedata.com/resource/pubmed/grant/R01 DA002277-33, http://linkedlifedata.com/resource/pubmed/grant/T32 GM007546-33, http://linkedlifedata.com/resource/pubmed/grant/T32 GM07546, http://linkedlifedata.com/resource/pubmed/grant/U19 GM061390-11, http://linkedlifedata.com/resource/pubmed/grant/UL1 RR024131, http://linkedlifedata.com/resource/pubmed/grant/UL1 RR024131-01
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pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/101231005
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Metformin, http://linkedlifedata.com/resource/pubmed/chemical/Mutant Proteins, http://linkedlifedata.com/resource/pubmed/chemical/Organic Cation Transport Proteins, http://linkedlifedata.com/resource/pubmed/chemical/SLC22A2 protein, human
pubmed:status	MEDLINE
pubmed:month	Jul
pubmed:issn	1744-6872
pubmed:author	pubmed-author:BrettClaire MCM, pubmed-author:BrownChalineC, pubmed-author:BurchardEsteban GEG, pubmed-author:CastroRichard ARA, pubmed-author:CheathamStephenS, pubmed-author:ChenLigongL, pubmed-author:ChenYingY, pubmed-author:ChoiJi HaJH, pubmed-author:GiacominiKathleen MKM, pubmed-author:HuangYongY, pubmed-author:LeabmanMaya KMK, pubmed-author:LiShuanglianS, pubmed-author:UrbanThomas JTJ, pubmed-author:YeeSook WahSW
pubmed:issnType	Print
pubmed:volume	19
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	497-504
pubmed:dateRevised	2011-9-26
pubmed:meshHeading	pubmed-meshheading:19483665-Biological Transport, pubmed-meshheading:19483665-Cell Line, pubmed-meshheading:19483665-Genetic Linkage, pubmed-meshheading:19483665-Homozygote, pubmed-meshheading:19483665-Humans, pubmed-meshheading:19483665-Kidney, pubmed-meshheading:19483665-Metformin, pubmed-meshheading:19483665-Mutant Proteins, pubmed-meshheading:19483665-Organic Cation Transport Proteins, pubmed-meshheading:19483665-Polymorphism, Single Nucleotide, pubmed-meshheading:19483665-Time Factors
pubmed:year	2009
pubmed:articleTitle	Effect of genetic variation in the organic cation transporter 2 on the renal elimination of metformin.
pubmed:affiliation	Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, California 94158, USA.
pubmed:publicationType	Journal Article, Clinical Trial, Research Support, N.I.H., Extramural