Source:http://linkedlifedata.com/resource/pubmed/id/19483089
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
9
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pubmed:dateCreated |
2009-8-18
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pubmed:abstractText |
This review briefly recapitulates the existing markers predictive of RA responsiveness to treatment, focusing on MTX alone or combined with a biologic. In addition to the demographic and clinical factors, an update is provided of the predictive biomarkers identified by large-scale gene and protein analyses that generated new insights into the ability of high-throughput analysis of biological systems to select new potential indicators. Among the large-scale analysis tools now available, pharmacogenetics and pharmacogenomics (including transcriptomic and proteomic approaches) have been shown to provide such new putative biomarkers of therapeutic responses.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1462-0332
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
48
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1021-8
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pubmed:meshHeading |
pubmed-meshheading:19483089-Antirheumatic Agents,
pubmed-meshheading:19483089-Arthritis, Rheumatoid,
pubmed-meshheading:19483089-Biological Markers,
pubmed-meshheading:19483089-Drug Therapy, Combination,
pubmed-meshheading:19483089-Humans,
pubmed-meshheading:19483089-Immunologic Factors,
pubmed-meshheading:19483089-Methotrexate,
pubmed-meshheading:19483089-Pharmacogenetics,
pubmed-meshheading:19483089-Prognosis,
pubmed-meshheading:19483089-Treatment Outcome
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pubmed:year |
2009
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pubmed:articleTitle |
Can rheumatoid arthritis responsiveness to methotrexate and biologics be predicted?
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pubmed:affiliation |
Inserm, Unité 905, France.
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pubmed:publicationType |
Journal Article,
Review,
Research Support, Non-U.S. Gov't
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